胡瑛

胡瑛，博士，讲师，硕士生导师。 2011年毕业于华东理工大学化学与分子工程学院，获工学学士学位，2017年毕业于韩国梨花女子大学纳米科学与化学系，获博士学位。主要从事荧光探针的设计合成及其应用于生物、环境及食品中重要物质检测的研究，在荧光探针的设计合成、荧光分析、以及活体细胞共聚焦成像等方面具有深厚的研究基础及丰富的经验，取得了较好的成果，主持国家自然科学基金面上项目一项，青年项目一项，省自然科学探索项目一项，同时参与了多项横向课题，以及多项韩国国家研究基金委的重要研究项目。并在光气与神经毒剂荧光探针、含氮爆炸物荧光探针、重金属离子和生物大分子荧光探针的开发等领域取得创新性成果。迄今为止，共发表SCI一区论文20余篇，其中以第一作者发表10余篇，主要发表在Chem. Soc. Rev.、Anal. Chem.、ACS Appl. Mater. Interfaces 、Sensor. Actuat. B-Chem等一区期刊上。 

学习及工作经历

2020-至今     浙江工业大学         讲   师

2018-2020    浙江工业大学         师资博士后       导师: 佘远斌 教授                              

2017-2018    韩国梨花女子大学  博士后             导师: Prof. Juyoung Yoon（韩国科学院院士）    

2012-2017    韩国梨花女子大学  博士(硕博连读) 导师: Prof. Juyoung Yoon（韩国科学院院士）                 

2007-2011    华东理工大学         应用化学（精细化工）  

😊  欢 迎 新 同 学 加 入 😊

国家级科研项目

1. 国家自然科学面上项目，多目标响应荧光薄膜传感器的构筑及对食品中多形态重金属的精准识别机制研究，2025/01-2028/12，50 万，在研，主持.

2. 国家自然科学青年科学基金项目，21807093，NMDA受体靶向的单胺氧化酶-A双光子荧光探针的构建及其生物成像的研究，2019/01-2021/12，25 万，结题，主持.

3. 浙江省自然科学基金探索项目，2023/01-2025/12, 10万，在研，主持.

横向项目 

1. 生物医药生产急需的高端试剂产业化项目任务，2020/12-2022/12，160 万，结题，参与.

2. 功能化金属纳米材料用于浓香型白酒主要风味化合物类的快速检测技术开发，2019/7-2022/7，50 万，结题，参与.

发表论文

1. Ying Hu, Shiman Guo, Junqian Peng, Yao Fan, Fang Wang, Lingmin Lu, Haiyan Fu, Xiaoqiang Chen, Yuanbin She, Ratiometric pyrene-based fluorescent sensor for on-site monitoring of formaldehyde in foods and living cells, Sensor. Actuat. B-Chem., 2023, 392, 134064. 

2. Ying Hu, Lingmin Lu, Yuxiao Wu, Yajing Li, Fang Wang, Xiaoqiang Chen, Haiyan Fu,  Yuanbin She, Bifunctional ratiometric fluorescent membrane containing pyrene-based  probe for visual monitoring and efficient removal of Al3+, , Sensor. Actuat. B-Chem., 2024, 413, 135856.

3. Ying Hu, Lu Shen, Yinan Zhang, Lingmin Lu, Haiyan Fu, Yuanbin She, A naphthalimide-based fluorescent probe for rapid detection of nitrite and its application in food quality monitoring, Anal. Chim. Acta,  2023, 1268, 341403.

4. Ying Hu, Lingmin Lu, Shiman Guo, Xiaolan Wu, Jiayi Zhang, Chunsong Zhou, Haiyan Fu, Yuanbin She, A reversible pyrene-based fluorescent probe for visual detection of cysteine in food samples, Sensor. Actuat. B-Chem., 2023, 382, 133534.

5. Ying Hu, Lixia Shao, Yao Fan, Lingmin Lu, Chunsong Zhou, Haiyan Fu, Yuanbin She, Colorimetric discrimination of tea polyphenols based on boronic acid sensor assembled with pH indicator, Dyes  Pigm., 2022, 203, 110326.

6. Ying Hu, Shuangshuang Long, Haiyan Fu, Yuanbin She,* Zhaochao Xu,* and Juyoung Yoon*, Revisit to Imidazolium Receptors for the Recognition of Anions: Highlighted Research During 2010-2019,Chem. Soc. Rev., 2020, 50, 589-612.

7. Ying Hu, Joonyoung F. Joung, Ji-Eun Jeong, Yerin Jeong, Han Young Woo, Yuanbin She, Sungnam Park,* and Juyoung Yoon*, 2-(Benzothiazol-2-yl)pyren-1-ol, a new excited state intramolecular proton transfer-based fluorescent sensor for nitroaromatic compounds, Sensor. Actuat. B-Chem., 2019, 280, 298-305. 

8. Nahyun Kwon, Ying Hu, Juyoung Yoon*, Fluorescent Chemosensors for Various Analytes Including Reactive Oxygen Species, Biothiol, Metal Ions, and Toxic Gases, ACS Omega, 2018, 3, 13731-13751.（共一）

9. Ying Hu, Xin Zhou, Hyeseung Jung, Sang-Jip Nam, Myung Hwa Kim*, Juyoung Yoon* Colorimetric and Fluorescent Detecting Phosgene by a Second-Generation Chemosensor, Anal. Chem. 2018, 90, 3382-3386. 

10. Ying Hu, Cheol Ho Heo, Gyoungmi Kim, Eun Jin Jun, Jun Yin, Hwan Myung Kim*, Juyoung Yoon*, One-Photon Two-Photon Sensing of Biothiols Using A Bis-Pyrene-Cu(II) Ensemble Its Application to Image GSH in the Cells Tissues, Anal. Chem. 2015, 87, 3308-3313. 

11. Ying Hu, Liyan Chen, Hyeseung Jung, Yiying Zeng, Songyi Lee, Kunemadihalli Mathada Kotraiah Swamy, Xin Zhou, Myung Hwa Kim*, and Juyoung Yoon*, Effective Strategy for Colorimetric and Fluorescence Sensing of Phosgene Based on Small Organic Dyes and Nanofiber Platforms, ACS Appl. Mater. Interfaces, 2016, 8, 22246–22252.

12. Ying Hu, Jun Yin, Juyoung Yoon*, A multi-responsive cyanine-based colorimetric chemosensor containing dipicolylamine moieties for the detection of Zn(II) Cu(II) ions, Sensor. Actuat. B-Chem., 2016, 230, 40-45. 

13. Ying Hu, Yinan Li, Joonyoung F. Joung, Jun Yin, Sungnam Park, Juyoung Yoon*, Myung Ho Hyun*, Iridium complex bearing urea groups as a phosphorescent chemosensor for chiral anion recognition, Sensor. Actuat. B-Chem., 2017, 241, 224–229. 

14. Ying Hu, Mahnseok Kye, Ji Young Jung, Yong-beom Lim, * Juyoung Yoon*, Design for a small molecule based chemosensor containing boron and pyridine moieties to detect HF, Sensor. Actuat. B-Chem., 2018, 255, 2621–2627. 

15. Ying Hu, Yifan Liu, Gyoungmi Kim, Eun Jin Jun, K. M. K. Swamy, Youngmee Kim, Sung-Jin Kim, Juyoung Yoon*, Pyrene based Fluorescent Probes for Detecting Endogenous Zinc Ions in Live Cells, Dyes Pigment., 2015, 113, 372-377. 

16. Jun Yin, Ying Hu, Juyoung Yoon*, Fluorescence probes bioimaging: alkali metals, alkaline earth metals protons, Chem. Soc. Rev., 2015, 44, 4619-4644. 

17. Zhixue Liu, Xin Zhou*, Yu Miao, Ying Hu, Nahyun Kwon, Xue Wu*, Juyoung Yoon*, A Reversible Fluorescent Probe for Real-time Quantitative Monitoring of Cellular Glutathione, Angew. Chem. Int. Ed., 2017, 56, 5812-5816. 

18. Jun Yin, Younghee Kwon, Dabin Kim, Dayoung Lee, Gyoungmi Kim, Ying Hu, Ji-Hwan Ryu* Juyoung Yoon*, A Cyanine Based Fluorescence Probe for Highly Selective Detection of Glutathione in Cell Cultures Live Mice Tissues, J. Am. Chem. Soc. 2014, 136, 5351-5318. 

19. Qingling Xu, Cheol Ho Heo, Jin A Kim, Hye Sue Lee, Ying Hu, Dayoung Kim, Kunemadihalli Mathada Kotraiah Swamy, Gyoungmi Kim, Sang-Jip Nam, Hwan Myung Kim*, Juyoung Yoon*, A Selective Imidazoline-2-Thione-Bearing Two-Photon Fluorescent Probe for Hypochlorous Acid in Mitochondria, Anal. Chem. 2016, 88, 6615-6620. 

20. Yao Fan, Min Yu, Ying Xu, Qin Wang, Ying Hu, Hai-Yan Fu*, Yuan-Bin She*. Nanoporphyrin/CdTe Quantum Dots: A Robust Tool for Effective Differentiation among DNA Structures. Sensor. Actuat. B-Chem., 2019, 281, 623−633.     

21. Junjie Jia, Meixia Wu, Songtao Wang, Xingcai Wang, Ying Hu, Hengye Chen, Yongjie Yu, Caihong Shen, Haiyan Fu,* Yuanbin She,* Colorimetric sensor array based on silver deposition of gold nanorods for discrimination of Chinese white spirits, Sensor. Actuat. B-Chem., 2020, 320, 128256. 

22. Hengye Chen, Ou Hu, Yao Fan, Lu Xu, Lei Zhang, Wei Lan, Ying Hu, Xingrui Xie, Lixia Ma, Yuanbin She, Haiyan Fu, Fluorescence paper-based sensor for visual detection of carbamate pesticides in food based on CdTe quantum dot and nano ZnTPyP, Food Chem., 2020, 327, 127075.

23. Yutao Yang, Fangjun Huo, Caixia Yin,* Ming Xu, Ying Hu, Jianbin Chao, Yongbin Zhang, Timothy E. Glass,* Juyoung Yoon*, A novel method for the synthesis of 1,2-benzisoxazoline-3-one its application to hypochlorite recognition, J. Mater. Chem. B. 2016, 4, 5101-5104. 

24. Fang Wang, Raju Nhakumar, Ying Hu, Dabin Kim, Kwan Mook Kim,* Juyoung Yoon*, BINOL-Based Chiral Receptors as Fluorescent Colorimetric Chemosensors for Amino Acids, J. Org. Chem. 2013, 78, 11571-11576.

本科专业课程：

      绿色有机催化及应用

      基础化学实验 I & II

      绿色化工专业实验 I

      绿色化学专业实验

研究生

以导师或二导指导博士研究生1名，硕士研究生12名，其中6名已顺利毕业，1名获校级优秀毕业生，1名获校优秀毕业论文。

本科生

指导本科生共9名，6名本科生已完成毕业论文，其中1名获省优秀毕业生，1名获校优秀毕业论文。