梁仁校

梁仁校，教授，硕士/博士生导师，华南理工大学有机化学博士毕业，主要从事过渡金属催化有机合成及不对称催化反应研究，先后在芳香化合物的不对称去芳构化反应、烯胺的不对称环化反应以及炔羰基化合物的不对称环化反应等方向开展研究工作，主持国家自然科学基金面上项目2项、青年项目1项、省属高校基本科研业务费B类项目1项、浙江省自然科学基金探索项目1项及企业合作项目1项。已在国内外期刊上发表学术论文50余篇，其中以第一作者或通讯作者身份在Acc. Chem. Res.、Angew. Chem. Int. Ed.、ACS Catal.、Chem. Sci.、Chem. Commun.、Org. Lett.等学术期刊上发表论文21篇，授权专利2件。入选浙江工业大学“青年英才支持计划”A类、浙江工业大学“十四五”高层次人才培育计划D类人才培育对象，获化学工程学院青年学者学术沙龙及青年英才、“新安杯”科研创新奖二等奖等奖励，担任《化工生产与技术》编委会青年委员；获得校级优秀班主任、院级优秀教师、化学工程学院教学大比武二等奖、优课优酬奖5课次、指导本科生参加第四届全国大学生化学实验创新设计大赛获全国总决赛一等奖。

本科生课程：《基础化学实验IIB》、《基础化学实验IIB-留学生》、《有机合成反应B》

研究生课程：《金属有机与均相催化》

[1] 国家自然科学基金(面上项目)，22371254，2024.01~2027.12，在研，项目负责人

[2] 国家自然科学基金(面上项目)，22071217，2021.01~2024.12，结题，项目负责人

[3] 浙江省自然科学基金(探索项目)，LY22B020008，2022.01~2024.12，结题，项目负责人

[4] 国家自然科学基金(青年项目)，21702184，2018.01~2020.12，结题，项目负责人

[5] 国家自然科学基金(面上项目)，21772175，2018.01~2021.12，结题，项目参与人

[6] Paxlovid关键中间体合成工艺路线研究(企业合作项目)，2022，项目负责人

[7] 新型可变色杀菌消毒产品的技术开发(企业合作项目)，2023，项目参与人

[8] 不对称氢化工艺(企业合作项目)，2022，项目参与人

[9] 九洲药业-不对称氢化工艺开发(企业合作项目)，2019，项目参与人

代表性研究成果：

[21] Song, Ling-Jie; Zhang, Xiao-Dong; Jin, Zheng-Hao; Liang, Ren-Xiao;* Jia, Yi-Xia;* Iron- Catalyzed Dearomatizing Reductive Cyclization of Arenes, Organic Letters, 2025, 27(6): 1390–1395.

[20] Liang, Ren-Xiao;* Cai, Hu-Jie; Mao, Ming-Hua; Bai, Xue-Pei; Du, Bao-Yu; Jia, Yi-Xia;* Copper-Catalyzed Dearomative [3+2] Annulation of Indoles with 2-Iodoacetic Acid, Organic Letters, 2024, 26(45): 9631–9636.

[19] Liang, Ren-Xiao;* Xie, Jia-Qi; Cai, Hu-Jie; Sun, Shuo; Wang, Jia-Yi; Deng, Wei-Chao; Jia, Yi-Xia;* Enantioselective Desymmetrization of 1,3-Dicarbonyl Compounds through Transition-Metal-Catalyzed Intramolecular Cyclization Reactions, ChemCatChem, 2024, 16(20): e202400947.

[18] Liang, Ren-Xiao;* Ding, Chao; Cai, Hu-Jie; Wang, Jia-Yi; Li, Qi-Chuang; Yu, Gao-Yang; Jia, Yi-Xia;* Pd-Catalyzed Enantioselective Desymmetrizing 1,7-Enyne Cycloisomerization of Alkyne-Tethered Cyclopentenes, Organic Letters, 2024, 26(20): 4400–4405.

[17] Jin, Cheng-An; Liang, Ren-Xiao;* Jia, Yi-Xia;* Silver-Catalyzed Dearomative [3+2] Spiroannulation of Aryl Oxamic Acids with Alkynes, Synthesis, 2024, 56(20): 3191–3198.

[16] Xie, Jia-Qi; Wang, Bing-Xia; Liang, Ren-Xiao;* Jia, Yi-Xia;* Copper-Catalyzed Asymmetric 1,2-Arylboration of Enamines: Access to Chiral Borate-containing 3,3’-Disubstituted Isoindolinones, Organic Biomolecular Chemistry, 2024, 22(30): 6085–6089.

[15] Wang, Bi; Gao, Jing-Kun; Sun, Shuo; Shen, Zhen-Lu; Yang, Yun-Fang; Liang, Ren-Xiao;* Jia, Yi-Xia;* Pd-Catalyzed Asymmetric Intramolecular Dearomatizing Reductive Heck Reaction of Indoles, Organic Letters, 2024, 26(18): 3739–3743.

[14] Gao, Wei-Yang; Yu, Gao-Yang; Li, Yan-Yu; Liang, Ren-Xiao;* Hong, Xin; Jia, Yi-Xia;* Palladium-Catalyzed Dearomative Heck/Suzuki Coupling of C2-Deuterated or C2-Nonsubstituted Indoles, Organic Letters, 2024, 26(12): 2359–2364.

[13] Lu, Jin-Bo; Xu, Xiao-Qiu; Ruan, Zi-Sheng; Liu, Kai; Liang, Ren-Xiao*; Jia, Yi-Xia*; Pd-Catalyzed Intramolecular Dearomative [4+2] Cycloaddition of Naphthalenes with Arylalkynes, Organic Letters, 2023, 25(45): 8139–8144.

[12] Liang, Ren-Xiao*; Tang, Heng-Wei; Liu, Jia-Liang; Xu, Jian-Feng; Chen, Ling-Jia; Jia, Yi-Xia*; Cobalt-Catalyzed Enantioselective Desymmetrizing Reductive Cyclization of Alkynyl Cyclodiketones, Chemical Science, 2023, 14(23): 6393–6398.

[11] Liang, Ren-Xiao; Jia, Yi-Xia*; Aromatic π-Components for Enantioselective Heck Reactions and Heck/Anion-Capture Domino Sequences, Accounts of Chemical Research, 2022, 55(5): 734–745.

[10] Liang, Ren-Xiao*; Chen, Jian-Fei; Huang, Ying-Ying; Yu, Ya-Ping; Zhang, Han-Yue; Song, Yu-Feng; Tsui, Gavin Chit*; Jia, Yi-Xia*; Enantioselective Pd-catalyzed dearomative reductive Heck and domino Heck–Suzuki reactions of 2-CF3-indoles, Chemical Communications, 2022, 58(42): 6200–6203.

[9] Liang, Ren-Xiao; Song, Ling-Jie; Lu, Jin-Bo; Xu, Wei-Yan; Ding, Chao; Jia, Yi-Xia*; Palladium-Catalyzed Enantioselective Heteroarenyne Cycloisomerization Reaction, Angewandte Chemie International Edition, 2021, 60(13): 7412–7417.

[8] Liang, Renxiao; Chen, Kai; Zhang, Qiaohui; Zhang, Jiantao; Jiang, Huanfeng; Zhu, Shifa*; Rapid Access to 2-Methylene Tetrahydrofurans and gamma-Lactones: A Tandem Four-Step Process, Angewandte Chemie International Edition, 2016, 55(7): 2587–2591.

[7] Liang, Ren-Xiao; Zhong, Chao; Liu, Zhi-Hong; Yang, Miao; Tang, Heng-Wei; Chen, Jian-Fei; Yang, Yun-Fang*; Jia, Yi-Xia*; Enantioselective Arylation of Tetrasubstituted Enamines: Access to Enantioenriched Indolenine and 1H-Indole Derivatives, ACS Catalysis, 2021, 11(3): 1827–1832.

[6] Liang, Ren-Xiao; Chen, Ru-Yi; Zhong, Chao; Zhu, Jia-Wen; Cao, Zhong-Yan; Jia, Yi-Xia*; 3,3'-Disubstituted Oxindoles Formation via Copper-Catalyzed Arylboration and Arylsilylation of Alkenes, Organic Letters, 2020, 22(8): 3215–3218.

[5] Liang, Ren-Xiao; Xu, Deng-Yun; Yang, Fu-Ming; Jia, Yi-Xia*; A Pd-Catalyzed Domino Larock Annulation/Dearomative Heck Reaction, Chemical Communications, 2019, 55(53): 7711–7714.

[4] Liang, Ren-Xiao; Wang, Ke; Wu, Quan; Sheng, Wei-Jian; Jia, Yi-Xia*; Palladium-Catalyzed Dearomative Arylvinylation Reaction of Indoles with N‑Arylsulfonylhydrazones, Organometallics, 2019, 38(20): 3927–3930.

[3] Weng, Jian-Quan; Xing, Ling-Ling; Hou, Wen-Ren; Liang, Ren-Xiao*; Jia, Yi-Xia*; Palladium-Catalyzed Dearomative Arylphosphorylation of Indoles, Organic Chemistry Frontiers, 2019, 6(10): 3577–3580.

[2] Liang, Ren-Xiao; Wang, Ke; Song, Ling-Jie; Sheng, Wei-Jian; Jia, Yi-Xia*; Synthesis of Tetracyclic Indolin-3-ones through Pd-Catalyzed Intramolecular Deacetylative Dearomatization of 3-Acetoxy-indoles, RSC Advances, 2019, 9(25):13959–13967.

[1] Liang, Ren-Xiao; Yang, Run-Ze; Liu, Ren-Rong; Jia, Yi-Xia*; Palladium-Catalyzed Asymmetric Dearomative Alkenylation of Indoles through a Reductive-Heck Reaction, Organic Chemistry Frontiers, 2018, 5(11):1840–1843.

授权专利：

[2] 一种含硼吲哚啉酮的制备方法，201911309561.9，2022.7.8

[1] 一种手性吲哚-2,3-并八元碳环化合物的制备方，202011448322.4，2022.11.4

* 指导或协助指导三十余名本科生完成毕业论文

* 作为第一或第二导师指导研究生二十余名

* 担任本科生2017级化工1701班、2021级化工2103班班主任

* 第一指导老师指导本科生参加第四届全国大学生化学实验创新设计大赛，获全国总决赛一等奖

(项目名称：钯-手性磷酸接力催化的一锅三步串联反应合成手性四氢喹啉；成员：钟哲、金张灵、史丽娟)