LINGYU ZHU

Biography

Professor Lingyu Zhu is vice department head of Chemical Engineering department. Her research covers simulation and optimization, analysis, and fault diagnosis of various traditional industrial processes, as well as modeling and solving of new unit operations, industrial process analysis.

Educational Background

September 1989 to June 1993, Bachelor of Engineering in Chemical Engineering, Zhejiang University.

September 1993 to June 1996, Master of Engineering in Chemical Engineering, Beijing University of Chemical Technology

March 2003 to December 2009, Doctor of Engineering in Control Theory and Control Engineering, Zhejiang University

July 2013 to February 2014, Visiting Scholar at the Chemical Engineering Department of Carnegie Mellon University

Work Experience:

From July 1996, Department of Chemical Engineering at Zhejiang University of Technology.

Undergraduate：

    Principle of Chemical Engineering

    Chemical Process Simulation

    Chemical Process Design

    Chemical Process System Engineering

    Introduction of Chemical Engineering

Master：

    Separation Process

Teaching and Research Awards:

In May 2013, selected for the Zhejiang Provincial Talents Training Program for Young and Middle-aged Academic Leaders.

In October 2012, awarded “Excellent Teacher in Zhejiang Province”.

In 2009, won the second prize of Zhejiang Provincial Science and Technology Progress Award for “the study on energy-saving and emissions reduction in large-scale chemical plants based on efficient combination separation technology”, ranked second.

In 2007, selected for the Zhejiang Provincial Youth Teachers Funding Program.

In 2005, selected for the third-level of the New Century Talent Project.

In 2005, second prize of the National Association of Higher Education Institutions for Outstanding Research Achievement in Chemical Engineering Education.

1. Jiayuan Wang, Luyao Liang, Lingyu Zhu. Solubility Measurement and Modeling of 5-Methyl-2-[(2-nitrophenyl) amino]-3-thiophenecarbonitrile (Y Form) in Pure and Binary Solvents. Journal of Chemical & Engineering Data, 2023, 68(4): 994-1001.

2. 陈朵朵, 王佳远, 周黎旸, 王树华, 祝铃钰.不确定性下基于柔性指数的计算机辅助制冷工质设计[J]. 高校化学工程学报, 2023, 37(2): 302-311.

3. Wang J, Smith R, Zhu L*. An adaptive refined grid search strategy for assessing operational flexibility and application on refrigerant selection[J]. AIChE Journal, 2022.

4. Wang J, Cao W, Wang J, Zhu L*. A novel Spherical Crystallization Method Using Pickering Emulsions[J]. Journal of Pharmaceutical Sciences, 2021.

5. Wang J, Chen D, Zhu L*. Integrated Working Fluids and Process Optimization for Refrigeration Systems Using Polar PC-SAFT[J]. Industrial & Engineering Chemistry Research, 2021, 60(48): 17640-17649.

6. Chenglin Zheng, Fei Zhao, Lingyu Zhu, Xi Chen∗, Flexibility index and design of chemical systems by cylindrical algebraic decomposition, Computers and Chemical Engineering,  2021(144), 107142

7. Shuhui Zhang, Fei Zhao, Chenglin Zheng, Lingyu Zhu, and Xi Chen*, SyPSE: A Symbolic Computation Toolbox for Process Systems Engineering Part II: Design for PSE Applications, Ind. Eng. Chem. Res. 2021, 60, 16317−16329

8. Zheng C, Zhao F, Zhu L*, Chen X*. Analytical solution of volumetric flexibility through symbolic computation [J]. Chemical Engineering Science, 2021, 239: 116643.

9. Udomwong K, Robin A, Kuprasertwong N, Padungwatanaroj O, Tula A, Zhu L, Zhou L, Wang S, Gani R*, Wang B. ProREFD: Tool for Automated Computer-Aided Refrigerant Design, Analysis, and Verification[M]//Computer Aided Chemical Engineering. Elsevier, 2021, 50: 457-462.

10. Kuprasertwong N, Padungwatanaroj O, Robin A, Udomwong K, Tula A, Zhu L, Zhou L, Wang B, Wang S, Gani R*. Computer-Aided Refrigerant Design: New Developments[M]//Computer Aided Chemical Engineering. Elsevier, 2021, 50: 19-24.

11. Zheng C, Zhao F, Zhu L, Chen X*. Flexibility index and design of chemical systems by cylindrical algebraic decomposition[J]. Computers & Chemical Engineering, 2021, 144: 107142.

12. Liu X, Mao Y, Yu S, Zhang H, Hu K, Zhu L, Ji J, Wang J*. An efficient and recyclable Pickering magnetic interface biocatalyst: application in biodiesel production[J]. Green Chemistry, 2021, 23(2): 966-972.

13. Zhang H, Yu S, Cao S, Liu X, Tang J, Zhu L, Ji J, Wang J*. Stabilizing triglyceride in methanol emulsions via a magnetic pickering interfacial catalyst for efficient transesterification under static conditions[J]. ACS omega, 2021.

14. Zhang S, Lou X, Xu R, Dai C, Xu N, Yan Q, Chen M, Sun X, Zhu L, Yun J*, Kirsebom H. Hydrophobic cryogels prepared via cryo-polymerization as oil carriers for biosynthesis of sophorolipids[J]. Biochemical Engineering Journal, 2020, 161: 107677.

15. Wang J, Cao W, Zhu L, Wang J, Lakerveld R*. Emulsion-assisted cooling crystallization of ibuprofen[J]. Chemical Engineering Science, 2020, 226: 115861.

16. Wang J, Li J, Cao W, Zhu L, Lakerveld R*. An ion-specific electrolyte non-random two-liquid segment activity coefficient model with improved predictive capabilities for aqueous electrolyte solutions[J]. Fluid Phase Equilibria, 2020, 517: 112605.

17. Wang J*, Zhu L, Lakerveld R. A Hybrid Framework for Simultaneous Process and Solvent Optimization of Continuous Anti-Solvent Crystallization with Distillation for Solvent Recycling[J]. Processes, 2020, 8(1): 63.

18. Zheng C, Zhao F, Zhu L, Chen X*. Flexibility Analysis of High-dimensional Systems via Cylindrical Algebraic Decomposition[M]//Computer Aided Chemical Engineering. Elsevier, 2020, 48: 1195-1200.

19. Zheng C, Zhao F, Zhu L, Chen X*. Operational flexibility analysis of high-dimensional systems via cylindrical algebraic decomposition[J]. Industrial & Engineering Chemistry Research, 2020, 59(10): 4670-4687.

20. 楼红枫，张舵，祝铃钰，李艳君，徐祖华，王凯，邵之江. 空分下塔动态机理模型约简及参数估计[A]. 中国自动化学会过程控制专业委员会、中国自动化学会.第31届中国过程控制会议（CPCC 2020）摘要集[C].中国自动化学会过程控制专业委员会、中国自动化学会:中国自动化学会过程控制专业委员会,2020:1.

21. Tao J, Wang J, Zhu L*, Chen X. Integrated design of multi-stage membrane separation for landfill gas with uncertain feed[J]. Journal of Membrane Science, 2019, 590: 117260.

22. 陶坚, 王建黎, 祝铃钰*. 两级空气膜分离系统的设计优化[J]. 高校化学工程学报, 2019, 33(6): 1482-1489.

23. Fanglin Shao, Xiang Li, Lingyu Zhu, Han Gong, Xi Chen*. Optimal Scheduling of the Multigrade Parallel Distillation Column System with a Continuous-Time Formulation. Industrial & Engineering Chemistry Research, 58, 23225-23237, (2019).

24. Jun Tang, Xue Zhou, Shixiong Cao, Lingyu Zhu, Lingling Xi, and Jianli Wang, Pickering Interfacial Catalysts with CO2 and Magnetic Dual Response for Fast Recovering in Biphasic Reaction[J], ACS Appl. Mater. Interfaces 2019, 11, 16156−16163.

25. Tingting Guan, Yawei Gao, Manman Pan, Yuwei Wu, Songhong Zhang, Linhong Xu,Lingyu Zhu, Junxian Yun, Slug flow hydrodynamics of immiscible fluids within a rectangular microchannel towards size-controllable fabrication of dextran-based cryogel beads[J], Chemical Engineering Journal，2019，369，116–123.

26. 贡晗, 李红阳, 施佳琪, 陶坚, 祝铃钰*. 基于可靠度的冷却水泵网络操作优化[J]. 高校化学工程学报, 2019, 33(3): 692-698.

27. 贡晗，李红阳，万德贵，章渊昶，纪彭，祝铃钰*，泵能效评估系统在循环水系统管理中的应用，计算机与应用化学，2019, 36(5):555-557.

28. Fei Zhao, Chenglin Zheng, Shuhui Zhang, Lingyu Zhu, Xi Chen*. Quantification of process flexibility via space projection. AIChE Journal, 65(10): e16706, (2019).

29. 韩建福,富敏霞,祝铃钰,贠军贤. L-苯丙氨酸制备的研究进展[J]. 生物加工过程, 2019, 17(2):117-124.

30. Jian Tao, Jianli Wang, Lingyu Zhu*, Xi Chen. Integrated design of multi-stage membrane separation for landfill gas with uncertain feed. Journal of Membrane Science. 590, 1-17, 2019

31. 富敏霞，祝铃钰，贠军贤，乳酸脱氢酶的分离纯化及其催化合成苯乳酸的研究进展，化工进展，2018, 37(12), 4814-4818

32. Zhao, fei; chen, xi; zhu, lingyu, a novel method to find all physical solutions of constrained chemical engineering models in polynomial equations, Industrial & Engineering Chemistry Research, 57(18): 6377-6390, 2018

33. Zheng, chenglin; chen, xi; zhu, lingyu, simultaneous design of pump network and cooling tower allocations for cooling water system synthesis, Energy, 150: 653-669, 2018   

34. Yan, wengang; zhu, yucai; zhu, lingyu, identification of systems with slowly sampled outputs using lpv model, Computers & Chemical Engineering, 112: 316-330, 2018   

35. Kang, jiayuan; zhu, lingyu; xu, shenjun, equation-oriented approach for handling the perturbed-chain saft equation of state in simulation and optimization of polymerization processes, Industrial & Engineering Chemistry Research, 57(13): 4607-4622, 2018

36. Luo, yingyan; zhang, qi; zhu, lingyu, optimal operation of parallel distillation systems with multiple product grades: an industrial case study, Computers & Chemical Engineering, 111: 210-224, 2018   

37. Fei Zhao, Xi Chen and Lingyu Zhu. Process Analysis on Multiple Solutions of Semi-algebraic Systems[C]// Proceedings of the 27th European Symposium on Computer Aided Process Engineering – ESCAPE 27 , 2017, Spain, Barcelona, 2059~2064

38. 祝铃钰，施佳琪，郑成霖，陈曦，离心泵网络的节能设计与操作优化：综述与展望，高校化学工程学报，31(6)，1245-1258, 2017

39. Fei Zhao, Xi Chen, Lingyu Zhu, A hybrid numerical-symbolic solving strategy for equation-oriented process simulation and optimization, AIChE Journal, 63(7):2764-2780, 2017  

40. Weiyu Jian, Lingyu Zhu, Zuhua Xu, Xi Chen*, A variable selection method for soft sensor development through mixed integer quadratic programming, Chemometrics and Intelligent Laboratory Systems, 167, 85–95, (2017).

41. Danyan Zhou, Kai Zhou, Lingyu Zhu, Jun Zhao, Zuhua Xu, Zhijiang Shao, Xi Chen*, Optimal Scheduling of Multiple Sets of Air Separation Units with Frequent Load-change Operation, Separation and Purification Technology, 172, 178–191, (2017).

42. Yun, Junxian; Lou, Xiaoling; Han, Jianfu, Guan, Jintao, Zhu, Lingyu，Separation of antibodies and albumin proteins from cattle serum by monolithic cryogels, New Biotechnology. 33(S): S204-S205, JUL 25 2016  

43. Shan, Lishen, Gao, Yunling; Zhang, Yuanchang, Yu, Wubin, Yang, Yujun, Shen, Shaochuan, Zhang, Songhong, Zhu, Lingyu, Xu, Linhong, Tian, Bing, Fabrication and Use of Alginate-Based Cryogel Delivery Beads Loaded with Urea and Phosphates as Potential Carriers for  Bioremediation, 250th National Meeting of the American-Chemical-Society (ACS), Boston, MA, AUG 16-20, 2015 Industrial & Engineering Chemistry Research，55(28): 7655-7660, 2016  

44. Zhao, Fei; Chen, Xi; Zhu, Lingyu,Simplification of Equation-Oriented Models through the Digraph Method, 26th European Symposium on Computer Aided Process Engineering (ESCAPE) , Portoroz, SLOVENIA, JUN 12-15, 2016, 26th European Symposium On Computer Aided Process Engineering (Escape), Computer Aided Chemical Engineering, 38A: 973-978, 2016

45. 孙蒋子豪，李红阳，祝铃钰，热虹吸式再沸器换热量软测量模型，计算机与应用化学，33(12)，1267-1271

46. Ma, Yannan; Weng, Jinzu; Shao, Zhijiang, Chen, Xi, Zhu, Lingyu, Zhao, Parallel Computation Method for Solving Large Scale Equation-oriented Models,12th International Symposium on Process Systems Engineering (PSE) / 25th European Symposium on Computer Aided Process Engineering (ESCAPE),Copenhagen, Denmark, May 31-Jun 04, 2015 Computer Aided Chemical Engineering

47. Qiwen Fu, Lingyu Zhu*, Xi Chen., Complete Equation-Oriented Approach for Process Analysis and Optimization of a Cryogenic Air Separation Unit, Industrial & Engineering Chemistry Research, 54,12096-12107, (2015).

48. Liuzhen Jiang, Kai Zhou, Lingyu Zhu*. Equation-oriented Modeling of Multi-stream Heat Exchanger in Air Separation Units, Computer Aided Chemical Engineering, 37, 371-376, (2015).

49. W Chen , Z Shao, L Zhu, X Chen, Homotopy with second-order correction based backtracking method for chemical process simulation, Industrial & Engineering Chemistry Research, 2014, 53,15080-15088,

50. W Chen , L Zhu, X Chen, Z Shao, Sensitivity Embedded Homotopy-Based Backtracking Method for Chemical Process Simulation，10th IEEE International Conference on Control & Automation，June 12-14, 2013, Hangzhou, China  

51.  徐申骏,祝铃钰*,陈曦，基于联立法的PC-SAFT状态方程模型,计算机与应用化学, 32（12），1453-1456, (2015).

52. 简葳玙、徐祖华、祝铃钰、陈曦，MC-UVE-GA-PLS算法用于精馏软测量辅助变量选择，计算机与应用化学, 11期, 1343-1346, （2015）

53. 张沅、章渊昶、祝铃钰*，基于分析的真空精馏系统操作优化，计算机与应用化学, 32(12), 1479-1482,（2015）

54. 祝铃钰*, 姜波, 任奕丞,基于集合算法的复杂精馏塔建模与求解,浙江工业大学学报,2014, 42（2）: 152-156

55. 祝铃钰*, 李建辉, 陈平,基于火用分析改造热泵精馏流程的设计方法，浙江工业大学学报，2014, 42（5）:483-486

56. W Chen, L Zhu, X Chen, Z Xu, Z Shao, Sensitivity-based Mnemonic Enhancement Optimization (S-MEO) for Real-time Optimization of Chemical Process, Proceedings of the 23rd European Symposium on Computer Aided Process Engineering

57. Chen, Xi; Li, Zhaohua; Wan, Wei; Zhu, Lingyu; *Shao, Zhijiang A master-slave solving method with adaptive model reformulation technique for water network synthesis using MINLP, Separation and purification technology, 2012, 98, 516-530

58.  李德新,姜波,任奕丞,祝铃钰,蒋鹏飞,周立芳,基于集合算法的高纯度精馏塔分段建模方法, 化工学报, 2012,63（9），2710-2715

59. 祝铃钰,李德新,任奕丞,陈曦, Lorenz T. Biegler, Aggregate models based on wave propagation theory for high purity distillation columns, Computer Aided Chemical Engineering, 2012, 31, 1587- 1591

60. 祝铃钰，杨巧玉，陈进中，陈平，郑国渠，基于超结构模型的铅阳极泥纸杯锑白工艺水网络优化，中国有色金属学报，2012，22（1）,592-598；

61. Lingyu Zhu, Dexin Li, Yichen Ren, Xi Chen, Lorenz T. Biegler.Aggregate models based on wave propagation theory for high purity distillation columns. 11th International Symposium on Process Systems Engineering. 2012. Accepted

62. 祝铃钰, 周莉芳,钱积新.热耦合空分流程变负荷特性分析与模拟方法.化工学报, 2011, 62(8), 2232-2237

63. Zuhua Xu, Jun Zhao, Xi Chen, Zhijiang Shao, Jixin Qian, Lingyu Zhu, Zhiyong Zhou, Haizhong Qin, Automatic load change system of cryogenic air separation process, Separation and Purification Technology, 2011, 81(3), 451-465.

64. Daqing Tian, Lingyu Zhu, Xi Chen, et. al. Nested Heuristic and Gradient-based Method for Generalized Disjunctive Programming，Computer Aided Chemical Engineering，2010

65. Daqing Tian, Lingyu Zhu, Xi Chen, et. al. Object-Oriented Disjunctive Programming with a Nested Heuristic and Gradient-Based Solver for Chemical Process Synthesis，Industrial & Engineering Chemistry Research, 2010, 49, 1779–1791

66.  俞晓梅，祝铃钰，张云，对界定塔板喷射液泛限的另类探讨，化学工程，2010，38（10），197-199

67.  梅诗宇，任健，祝铃钰，姚克俭，气提法脱除废水中的丙烯腈，化工进展，2010，29（7），1201-1204；

68. 李大刚，祝铃钰.基于过程数据的空分系统参数估计.计算机与应用化学，2010，27(3)：55-58

69. Lingyu Zhu, Zhiqiang Chen, Xi Chen, Zhijiang shao, Jixin Qian, Simulation and optimization of cryogenic air separation units using a homotopy-based backtracking method, Separation and Purification Technology, 2009, 67(3), 262-270

70. 祝铃钰, 陈智强, 陈曦, 邵之江, 钱积新. 大规模变工况流程模拟的回溯同伦法.高校化学工程学报, 2009, 23(4), 690-695

71. Lingyu Zhu, Xi Chen, Zhijiang Shao, Jixin Qian. Soft Sensor for Distillation Column Feeds.2009 Chinese Control and Decision Conference, June 17-19 2009, Guilin, China.

72.  陆晓艳, 祝铃钰, 姚克俭.多杂质水网络超结构模型及其同步设计法研究.化工环保, 2009, 29(3)，242-245

73. Daqing Tian, Lingyu Zhu, Xi Chen, Zhijiang shao, Jixin Qian.Nested Heuristic and Gradient-based Method for Generalized Disjunctive Programming. 10th International Symposium on Process Systems Engineering - PSE2009, August 16-20, 2009, Salvador, Brazil.

74.  张颂红，祝铃钰,章渊昶，姚克俭，组合分离技术的研究及其在化工装置节能降耗中的应用，化工进展（增刊），2009

75. Xi Chen, Zhaohua Li, Jing Yang, Zhijiang Shao, Lingyu Zhu, Nested Tabu Search (TS) and Sequential Quadratic Programming (SQP) Method, Combined with Adaptive Model Reformulation for Heat Exchanger Network Synthesis (HENS), Industrial & Engineering Chemistry Research, 2008, 47, 2320-2330

76. 王吉林, 祝铃钰, 许轶, 姚克俭.基于OPC通讯的实时流程模拟技术研究.现代化工, 2008（增刊）, 174-176

77. 张正江, 祝铃钰, 邵之江, 陈曦, 钱积新.基于大规模严格机理模型的数据校正.高校化学工程学报, 2008, 22（5）, 877-882

78. Zhaohua Li, Lingyu Zhu, Daqing Tian, Xi Chen. A nested method for water networks synthesis.18th International Congress of Chemical and Process Engineering , Aug. 2008, Prague, Czech.

79. Lingyu Zhu, Zhiqiang Chen, Xi Chen, Zhijiang shao, Jixin Qian. An algebraic homotopy based backtracking method for simulation of air separation process under widely varying load conditions.18th International Congress of Chemical and Process Engineering, 2008, Czech, Prague

80. 姚克俭, 王良华, 祝铃钰, 俞晓梅.Improving Efficiency of Multiple Downcomer Tray Performance by Various Tray Structure Modifications. SESSION 4, DISTILLATION SYMPOSIUM，2007 AIChE Meeting, 2007

81. 俞晓梅, 祝铃钰, 姚克俭. Study on Two Phase Flow in Tray Downcomers – Backmixing and Choking Tests. SESSION 3, DISTILLATION SYMPOSIUM，2007 AIChE Meeting, 2007

82. 祝铃钰，钱积新.多元精馏热力学性质自适应神经－模糊模型.全国第三届化学工程与生物化工年会，2006，光盘版，K009

83. 刘保柱,姚克俭,祝铃钰，理想热耦合精馏的特性研究，化工进展（增刊），2005

84. Lingyu Zhu，Xiaomei Yu, Kejian Yao，Lianghua Wang. Promotions for Further Improvements in Multiple Downcomer Tray Performance. Ind. Eng. Chem. Res.. 2004.43(20) 6484-6489.