期刊论文 (# 共同一作;*通讯作者)
51. Huitian Lin#, Cheng Zhu#, Tianfeng Shang#, Ning Zhu, Kang Lin, Chengyun Zhang, Xiang Shao*, Xu-Dong Wang*, Hongliang Duan*. HighPlay:Cyclic Peptide Sequence Design Based on Reinforcement Learning and Protein Structure Prediction,Journal of Medicinal Chemistry, 2025, 68(11): 12047–12057.
50. Yunhui Zhang, Bowei Zhang, Xiaoxia Liu, Xiang Li, Fan Wei, Lingda Zhao, Huan Lv, Xudong Wang, Jin Wang, Jing Wu, Yan Zhang, Shuo Wang*. Gastrointestinal distribution and in vitro-microbial biotransformation of chlorogenic acid, Food Science and Human Wellness, 2024, https://doi.org/10.26599/FSHW.2024.9250312
49. Zhihao Su, Yejian Wu, Kaiqiang Cao, Jie Du, Lujing Cao, Zhipeng Wu, Xinyi Wu, Xinqiao Wang,Ying Song, Xudong Wang*, Hongliang Duan*. APEX-pHLA: A novel method for accurate predictionof the binding between exogenous short peptides and HLA class I molecules, Methods, 2024, 228: 38-47.
48. Tianqi Cai, Xiaoxue Xu, Ling Dong, Shufei Liang, Meiling Xin, Tianqi Wang, Tianxing Li, Xudong Wang, Weilong Zheng, Chao Wang, Zhengbao Xu, Meng Wang, Xinhua Song, Lingru Li*, Jingda Li*, Wenlong Sun*.Oroxin A from Oroxylum indicum improves disordered lipid metabolism by inhibiting SREBPs in oleic acid-induced HepG2 cells and high-fat diet-fed non-insulin-resistant rats, Heliyon, 2024, 10 (7): e29168.
47. Xu-Dong Wang*, Zhi-Hao Su, Jie Du, Wei-Jia Yu, Wen-Long Sun*. Site-selective Fatty Acid Chain Conjugation of the N-terminus of the Recombinant Human Granulocyte Colony-Stimulating Factor,Frontiers in Bioengineering and Biotechnology,2024, 12:1360506.
46. Shu-Chang Wang, Xu-Dong Wang, Xin-Nan Teng, Jian-Ying Dai, Yue-Sheng Dong, Heng-Li Yuan, Zhi-Long Xiu*. Fatty acid chain modification of loxenatide and its kinetics in a continuous flow microchannel reactor, Process Biochemistry, 2023, 124: 259-268.
45. Xu-Dong Wang*, Wei-Jia Yu, Jia-Hui Liu, Jie Du, Kang-Nan Chen, Qin-Qin Hu, Wen-Long Sun*, Guo-Qing Ying*. Preparation and characterization of site-specific fatty chain-modified recombinant human granulocyte colony stimulating factor, Frontiers in Bioengineering and Biotechnology, 2022, 10: 923059.
44. 王旭东,刘家辉,陈康楠,梅建凤,易喻,应国清*. 长效化重组人粒细胞集落刺激因子的研究进展,药学学报,2022, 57(04): 875-883.
43. Jingda Li*, Tao Xiong, Tianqi Wang, Meng Wang, Chao Wang, Fuyuan Yang , Xudong Wang, Zhijian Tan*, Wenlong Sun*.Baicalein targets CD36 to prevent foam cell formation by suppressing the excessive uptake of oxLDL and accelerating ABCA1-mediated cholesterol efflux in oxLDL-induced THP-1 macrophages,Journal of Functional Foods, 2022,97: 105253.
42. Shu-Chang Wang, Xin-Nan Teng, Xu-Dong Wang, Yue-Sheng Dong, Heng-Li Yuan, Zhi-Long Xiu*. Recycling reaction and separation for FACylation of loxenatide by trade-off between miscibility and immiscibility of reactants and product in methanol solution, Journal of Chromatography A, 2022, 1676:463239.
41. Jianfeng Mei, Shaofen Cai, Yu Yi, Yanlu Zhang, Xudong Wang, Guoqing Ying*. Study of the fibrinolytic activity of serrapeptase and its in vitro thrombolytic effects, Brazilian Journal of Pharmaceutical Sciences, 2022, 58: e201004.
40. Yu Yi*, Ting Huang, Yunxia Xu, Jianfeng Mei, Yanlu Zhang, Xudong Wang, Jianshu Chen and Guoqing Ying*. Preparation and properties of N-glycosylated chitosan_polyvinyl alcohol hydrogels for use in wound dressings, Journal of Applied Biomaterials & Functional Materials, 2022, DOI: 10.1177/22808000221101809.
38. 潘多涛,王旭东,史洪岩,修志龙*.生物基 1, 3-丙二醇连续发酵过程的稳态分析与反馈控制,化工学报,2022,73(5): 2094-2100.
37. Duo-Tao Pan, Xu-Dong Wang, Jia-Bing Wang, Hong-Yan Shi, Guo-Gang Wang, Zhi-Long Xiu*. Optimization and feedback control system of dilution rate for 1,3-propanediol in two-stage fermentation, Biotechnology Progress, 2022,38:e3225.
36. Huiju Zhang, Min Shi, Shuting Su, Sikai Zheng, Miao Wang, Jun Lv, Xudong Wang, Quan Yang, Hongyang Gao*. Whole-genome methylation analysis reveals epigenetic differences in the occurrence and recovery of hyperhydricity in Dendrobium officinale plantlets, In Vitro Cellular & Developmental Biology – Plant, 2022, 58:290-301.
35. Yu Yi*, Jianming Hu, Shenwei Ding, Jianfeng Mei, Xudong Wang, Yanlu Zhang, Jianshu Chen, Guoqing Ying*. A preparation strategy for protein-oriented immobilized silica magnetic beads with spy chemistry for ligand fishing,Journal of Pharmaceutical Analysis, 2022, 12:415-423.
34. Jianfeng Mei, Xia Wu, Shujing Zheng,Yu Yi, Xudong Wang, Guoqing Ying*. Production of bilirubin by biotransformation of biliverdin using recombinant Escherichia coli cells, Bioprocess and Biosystems Engineering, 2022, 45(3):563-571.
33. Xu-Dong Wang#, Chun-Yan Hu #, Chao Qin, Yue-Sheng Dong, Guo-Qing Ying, Zhi-Long Xiu*, Zhi-Guo Su. Simultaneous solid–liquid separation and primary purification of clavulanic acid from fermentation broth of Streptomyces clavuligerus using salting-out extraction system, Engineering in Life Sciences, 2021, 21:643–652.
32. Wen-Long Sun, Xin-Yu Li, Hao-Yue Dou, Xu-Dong Wang, Jing-Da Li, Liang Shen*, Hong-Fang Ji*. Myricetin supplementation decreases hepatic lipid synthesis and inflammation by modulating gut microbiota, Cell Reports, 2021, 36(9):109641.
31. Jingda Li*, Tianqi Wang, Panpan Liu, Fuyuan Yang, Xudong Wang, Weilong Zheng, Wenlong Sun*. Hesperetin ameliorates hepatic oxidative stress and inflammation via the PI3K/AKT-Nrf2-ARE pathway in oleic acid-induced HepG2 cells and a rat model of high-fat diet-induced NAFLD,Food & Function, 2021,12, 3898-3918.
30. Wenlong Sun*, Panpan Liu, Bendong Yang, Meng Wang, Tianqi Wang, Wenbo Sun, Xudong Wang, Weilong Zheng, Xinhua Song*, Jingda Li*. A network pharmacology approach: inhibition of the NF-κB signaling pathway contributes to the NASH preventative effect of an Oroxylum indicum seed extract in oleic acid-stimulated HepG2 cells and high-fat diet-fed rats, Phytomedicine, 2021, 88, 153498.
29. Jianfeng Mei, Xiaoyun Zhao, Yu Yi, Yanlu Zhang, Xudong Wang, Guoqing Ying*. Preparation of astaxanthin by lipase-catalyzed hydrolysis from its esters in a slug-flow microchannel reactor, Process Biochemistry, 2020, 98: 241-246.
28. Wenlong Sun*, Panpan Liu, Tianqi Wang, Xu-Dong Wang, Weilong Zheng, Jingda Li*. Baicalein reduced hepatic fat accumulation by activating AMPK in oleic acid-induced HepG2 cells and high-fat diet-induced non-insulin resistant mice,Food & Function, 2020, 11(1): 711-721.
27. Shu-Chang Wang #, Xu-Dong Wang#, Xin-Nan Teng, Zhi-Long Xiu*. Chemical modification of recombinant hirudin with palmitic acid in mixed aqueous-organic solutions,Process Biochemistry, 2019, 55:85-92.
26. Liaqat Zeb, Xu-Dong Wang, Wei-Long Zheng, Xin-Nan Teng, Muhammad Shafiq, Ying Mu, Zhan-You Chi, Zhi-Long Xiu*. Microwave-assisted three-liquid-phase salting-out extraction of docosahexaenoic acid (DHA)-rich oil from fermentation broths of Schizochytrium limacinium SR21, Food and Bioproducts Processing, 2019, 118: 237-247.
25. Yue-Sheng Dong*, Fan Yang, Wen-Cai Liu, Xu-Dong Wang, Yan Xing, Zhi-Long Xiu. Separation and purification of wortmannilactone analogues by three-liquid-phase salting-out extraction coupled with column chromatography, Separation and Purification Technology, 2019,224:397-404.
24. Duo-Tao Pan, Xu-Dong Wang, Hong-Yan Shi, De-Cheng Yuan, Zhi-Long Xiu*. Ensemble optimization of microbial conversion of glycerol into 1, 3-propanediol by Klebsiella pneumoniae, Journal of Biotechnology, 2019, 301: 68-78.
23. Guo-Qing Ying, Xing-Ru Lu, Jian-Feng Mei, Yan-Lu Zhang, Jian-Shu Chen, Xu-Dong Wang, Zhi-Ming Ou, Yu Yi*. A structure-activity relationship of a thrombin-binding aptamer containing LNA in novel sites, Bioorganic & Medicinal Chemistry, 2019, 27(14): 3201-3207.
22. Xu-Dong Wang, Ning-Ning Wei, Shu-Chang Wang, Heng-Li Yuan, Feng-Ying Zhang, Zhi-Long Xiu*. Kinetic optimization and scale up of site-specific thiol-PEGylation of loxenatide from laboratory to pilot scale, Industrial & Engineering Chemistry Research, 2018, 57 (44): 14915-14925.
21. Xudong Wang, Shuchang Wang, Duotao Pan, Kairong Qin, Hengli Yuan, Fengying Zhang, Yundong Sun, Zhilong Xiu*. Combined optimization of N-terminal site-specific PEGylation of recombinant hirudin using response surface methodology and kinetic analysis, Engineering in Life Sciences, 2018, 18 (8): 611-621.
20. 胡春燕,王旭东*,秦超,董悦生,修志龙. 克拉维酸钾一步结晶工艺优化,高校化学工程学报,2018, 32 (4) : 910-917.
19. Ling Yan, Ya-Qin Sun, Xu-Dong Wang, Hong-Xin Fu, Ying Mu, Zhi-Long Xiu*. Partition behavior of monocarboxylic acids in salting-out extraction systems of monohydric alcohols and dipotassium phosphate, Separation and Purification Technology, 2018, 199:351-358.
18. Weilong Zheng, Jingda Li, Xudong Wang, Yanping Yuan, Jianing Zhang, Zhilong Xiu*. Effects of Antarctic krill docosahexaenoic acid on MCF-7 cell migration and invasion induced by the interaction of CD95 with caveolin-1, Life Sciences, 2018, 192: 270-277.
17. Duo-Tao Pan,Xu-Dong Wang,Hong-Yan Shi,De-Cheng Yuan, Zhi-Long Xiu*. Dynamic flux balance analysis for microbial conversion of glycerol into 1,3-propanediol by Klebsiella pneumoniae, Bioprocess and Biosystems Engineering, 2018, 41(12):1793-1805.
16. 鄢凌, 傅宏鑫, 王旭东, 孙亚琴, 戴建英, 修志龙*. 生物基有机酸的提取分离技术研究进展,过程工程学报, 2018, 18(1): 1-10.
15. Xudong Wang, Li Lv, Kairong Qin, Hengli Yuan, Fengying Zhang, Guohui Chen, Zhilong Xiu*. Effects of linear and branched polyethylene glycol on PEGylation of recombinant hirudin: Reaction kinetics and in vitro and in vivo bioactivities, Process Biochemistry, 2017, 63:154-162.
14. Hongxin Fu#, Xudong Wang#, Yaqin Sun, Ling Yan, Juntao Shen, Jufang Wang, Shang-Tian Yang, Zhilong Xiu*. Effects of salting-out and salting-out extraction on the separation of butyric acid, Separation and Purification Technology, 2017, 180:44-50.
13. Xudong Wang, Xueqin Li, Jun Zhao, Li Lv, Kairong Qin, Hengli Yuan, Zhi-Long Xiu*. In situ PEGylation of recombinant hirudin on an anion exchange chromatography column, Process Biochemistry, 2017, 55:162-171.
12. Weilong Zheng, Xudong Wang, Wenjing Cao, Bowen Yang, Ying Mu, Yuesheng Dong, Zhilong Xiu*. E-configuration structures of EPA and DHA derived from Euphausia superba and their significant inhibitive effects on growth of human cancer cell lines in vitro, Prostaglandins, Leukotrienes & Essential Fatty Acids, 2017, 117: 47-53.
11. Juntao Shen, Li Lv, Xudong Wang, Zhilong Xiu*, Guoqiang Chen. Comparative analysis of CRISPR-Cas systems in Klebsiella genomes. Journal of Basic Microbiology, 2017, 57: 325-336.
10. 胡春燕,秦超,王旭东,董悦生,修志龙*,李树有, 冯涛, 王启斌. 克拉维酸在乙酸乙酯中的稳定性, 高校化学工程学报, 2017, 31(2):270-275.
09. 姜莉莉,周瑾洁,王旭东,孙亚琴,修志龙*. 微生物菌群发酵生产化学品的研究进展,生物工程学报, 2016, 32(11): 1496-1506.
08. 周瑾洁,王旭东,孙亚琴,修志龙*. 生物基化学品的微生物电合成研究, 化工进展, 2016, 35(10):3005-3015.
07. Xu-Dong Wang, Hu Teng, Jing-Jing Hu, Zhi-Long Xiu*. PEGylation of recombinant hirudin in mixed aqueous-organic solutions, Process Biochemistry, 2015, 50: 367-377.
06. Xudong Wang, Jingjing Hu, Duotao Pan, Hu Teng, Zhilong Xiu*. PEGylation kinetics of recombinant hirudin and its application for the production of PEGylated HV2 species, Biochemical Engineering Journal, 2014, 85: 38-48.
05. 王旭东,李晓晖,苏志国,修志龙*. 蛋白质药物的聚乙二醇定点修饰策略与最佳位点,中国生物工程杂志,2010, 30 (4) : 101-109.
04. 孙丽慧,戴建英,王旭东,修志龙*. 两株Klebsiella pneumoniae 菌发酵生产2,3-丁二醇的比较,过程工程学报, 2010, 10 (3):588-592.
03. 孙丽慧,戴建英,王旭东,修志龙*. 发酵条件对产2,3-丁二醇Klebsiella pneumoniae 代谢的影响,食品与发酵工业, 2010, 36 (8):6-11.
02. Li-Hui Sun, Xu-Dong Wang, Jian-Ying Dai, Zhi-Long Xiu*. Microbial production of 2,3-butanediol from Jerusalem artichoke tubers by Klebsiella pneumoniae, Applied Microbiology and Biotechnology, 2009, 82: 847-852.
01. 孙丽慧,王旭东,戴建英,修志龙*. Klebsiella pneumoniae 发酵菊芋块茎生产2,3-丁二醇的初步研究,过程工程学报, 2009, 9 (1):161-164.