一,获奖
郑裕国, 胡忠策, 柳志强, 白骅, 陈正杰, 沈寅初. 1,3-二羟基丙酮微生物法生产技术开发及产业化. 中国石油和化学工业联合会, 2013年技术发明二等奖.(2/6)
二,发表的论文
[1]Hu Z.C, Dai H.W, Gu B.Q, Wang, Y. S, Liu, Z.Q*, Zheng Y.G. The combination of ultraviolet mutagenesis and PPX1 overexpression synergistically enhanced S-adenosyl-L-methionine synthesis in industrial Saccharomyces cerevisiae [J]. Enzyme Microb Technol, 2025, 185: 110591.2025-1-27
[2]Hu Z.C., Yang G.L., Chen J.Y., Tang H., Zou S.P., Xue, Y.P., *, Zheng Y.G. Structure-guided directed evolution of deacetylase leads to increased specificity of chloroacetamides and effective production of chloroamines. Biochemical Engineering Journal. 2024, 203:109214. 2024-1-3
[3]Hu Z.C., Tian Y.H., Yang J.L., Zhu Y.N., Zhou H.Y., Zheng Y.G., Liu Z.Q. * Research progress of l‑aspartate‑α‑decarboxylase and its isoenzyme in the β‑alanine synthesis. World Journal of Microbiology and Biotechnology.2023,39:42
[4]Hu Z.C., Zheng C.M, Tao Y.C., Wang S.N., Wang Y.S., Liu Z.Q.* , Zheng Y.G. Improving ATP availability by sod1 deletion with a strategy of precursor feeding enhanced S-adenosyl-L-methionine accumulation in Saccharomyces cerevisiae. Enzyme and Microbial Technology. 2023,164:110189
[5] Liu, D., Ke, X., Hu, Z.C.*, Zheng, Y.G. Improvement of pyrroloquinoline quinone-dependent D-sorbitol dehydrogenase activity from Gluconobacter oxydans via expression of Vitreoscilla hemoglobin and regulation of dissolved oxygen tension for the biosynthesis of 6-(N-hydroxyethyl)-amino-6-deoxy-α-L-sorbofuranose. Journal of Bioscience and Biotechnology. 2021,131(5):518-524
[6] Hu, Z.C., Li, W.J., Zou, S.P., Niu, K., Zheng, Y.G*.Mutagenesis of echinocandin B overproducing Aspergillus nidulans capable of using starch as main carbon source. Prep. Biochem. Biotechnol., 2020. 50(8), 745-752.
[7] Hu, Z.C., Zhao, Z.Y., Ke, X., Zheng, Y.G.* Repeated production of 6-(N-hydroxyethyl)-amino-6-deoxy-alpha-l-sorbofuranose by immobilized Gluconobacter oxydans cells with a strategy of in situ exhaustive cell regeneration. Bioprocess and Biosystems Engineering, 2020, 43, 1781-1789
[8] Liu, D., Hu, Z.C.*, Ke, X., Zheng, Y.G. Breeding of Gluconobacter oxydans with high PQQ-dependent D-sorbitol dehydrogenase for improvement of 6-(N-hydroxyethyl)-amino-6-deoxy-alpha-L-sorbofuranose production. Biochemical Engineering Journal, 2020, 161,107642
[9]Liu, D., Ke, X., Hu, Z.C.*, Zheng, Y.G. Combinational expression of D-sorbitol dehydrogenase and pyrroloquinoline quinone increases 6-(N-hydroxyethyl)-amino-6-deoxy-α-L-sorbofuranose production by Gluconobacter oxydans through cofactor manipulation, Enzyme Microb. Tech. 2020, 141:109670