梁仁校

       梁仁校，教授，硕士/博士生导师，化学工艺学科副主任

       华南理工大学有机化学博士毕业，主要从事过渡金属催化有机合成及不对称催化反应研究，先后在芳香化合物的不对称去芳构化反应、烯胺的不对称环化反应以及炔羰基化合物的不对称环化反应等方向开展研究工作，已在国内外期刊上发表学术论文五十余篇，其中以第一作者或通讯作者身份在Acc. Chem. Res.、Angew. Chem. Int. Ed.、ACS Catal.、Chem. Sci.、Chem. Commun.、Org. Lett.等学术期刊上发表论文二十余篇，授权专利3件。

       主持国家自然科学基金面上项目2项、青年项目1项、省属高校基本科研业务费B类项目（优秀青年科学家专项）1项、浙江省自然科学基金面上项目1项及企业合作项目多项；入选浙江工业大学“青年英才支持计划”A类、浙江工业大学“十四五”高层次人才培育计划D类人才培育对象，获化学工程学院青年学者学术沙龙及青年英才一等奖、三等奖、“新安杯”科研创新奖二等奖等奖励。担任《化工生产与技术》编委会青年委员，获得校级优秀班主任、院级优秀教师、化学工程学院教学大比武二等奖、优课优酬奖6课次、指导本科生参加第四届全国大学生化学实验创新设计大赛获全国总决赛一等奖。参编省部级重点教材1部《有机化学实验(双语版)》。

本科生课程：《有机合成反应B》、《化工综合创新实践》、《基础化学实验IIB》、《基础化学实验IIB-留学生》

研究生课程：《金属有机与均相催化》

[1] 国家自然科学基金(面上项目)，22371254，2024.01~2027.12，在研，项目负责人

[2] 国家自然科学基金(面上项目)，22071217，2021.01~2024.12，结题，项目负责人

[3] 浙江省自然科学基金(探索项目)，LY22B020008，2022.01~2024.12，结题，项目负责人

[4] 国家自然科学基金(青年项目)，21702184，2018.01~2020.12，结题，项目负责人

[5] 国家自然科学基金(面上项目)，21772175，2018.01~2021.12，结题，项目参与人

[6] 企业委托项目，2025.03~2025.12，项目负责人

[7] 企业委托项目，2022.01~2023.05，项目负责人

[8] 企业委托项目，2023.06~2023.12，项目参与人

[9] 企业委托项目，2022.01~2023.05，项目参与人

[10] 企业委托项目，2019.01~2019.08，项目参与人

[55] Jin, Cheng-An; Liu, Hao; Xie, Bo-Wen; Liang, Ren-Xiao;* Jia, Yi-Xia; Visible-light-induced Dearomative 1,4-Carbamoylpyridinylation of Nonactivated Naphthalenes, Org. Biomol. Chem. 2025, 23(23): 5576–5581.

[54] Lu, Jin-Bo; Wang, Yi-Fan; Xu, Xue-Ting; Wang, Bing-Xia; Liang, Ren-Xiao;* Jia, Yi-Xia;* Dearomative 1,6-Enyne Cycloisomerization of Alkyne-tethered Benzofurans and Indoles via a 6-endo-dig Cyclization, Chem. Commun. 2025, 61(42): 7616–7619.

[53] Song, Ling-Jie; Zhang, Xiao-Dong; Jin, Zheng-Hao; Liang, Ren-Xiao;* Jia, Yi-Xia;* Iron-Catalyzed Dearomatizing Reductive Cyclization of Arenes, Org. Lett. 2025, 27(6), 1390–1395.

[52] Liang, Ren-Xiao;* Cai, Hu-Jie; Mao, Ming-Hua; Bai, Xue-Pei; Du, Bao-Yu; Jia, Yi-Xia;* Copper-Catalyzed Dearomative [3+2] Annulation of Indoles with 2-Iodoacetic Acid, Org. Lett. 2024, 26(45), 9631–9636.

[51] Liang, Ren-Xiao;* Xie, Jia-Qi; Cai, Hu-Jie; Sun, Shuo; Wang, Jia-Yi; Deng, Wei-Chao; Jia, Yi-Xia;* Enantioselective Desymmetrization of 1,3-Dicarbonyl Compounds through Transition-Metal-Catalyzed Intramolecular Cyclization Reactions, ChemCatChem 2024, 16(20), e202400947.

[50] Liang, Ren-Xiao;* Ding, Chao; Cai, Hu-Jie; Wang, Jia-Yi; Li, Qi-Chuang; Yu, Gao-Yang; Jia, Yi-Xia;*Pd-Catalyzed Enantioselective Desymmetrizing 1,7-Enyne Cycloisomerization of Alkyne-Tethered Cyclopentenes, Org. Lett. 2024, 26(20), 4400–4405.

[49] Jin, Cheng-An; Liang, Ren-Xiao;* Jia, Yi-Xia;* Silver-Catalyzed Dearomative [3+2] Spiroannulation of Aryl Oxamic Acids with Alkynes, Synthesis 2024, 56(20), 3191–3198.

[48] Xie, Jia-Qi; Wang, Bing-Xia; Liang, Ren-Xiao;* Jia, Yi-Xia;* Copper-Catalyzed Asymmetric 1,2-Arylboration of Enamines: Access to Chiral Borate-containing 3,3’-Disubstituted Isoindolinones, Org. Biomol. Chem. 2024, 22(30), 6085–6089.

[47] Wang, Bi; Gao, Jing-Kun; Sun, Shuo; Shen, Zhen-Lu; Yang, Yun-Fang; Liang, Ren-Xiao;* Jia, Yi-Xia;*Pd-Catalyzed Asymmetric Intramolecular Dearomatizing Reductive Heck Reaction of Indoles, Org. Lett. 2024, 26(18), 3739–3743.

[46] Gao, Wei-Yang; Yu, Gao-Yang; Li, Yan-Yu; Liang, Ren-Xiao;* Hong, Xin; Jia, Yi-Xia;* Palladium-Catalyzed Dearomative Heck/Suzuki Coupling of C2-Deuterated or C2-Nonsubstituted Indoles, Org. Lett. 2024, 26(12), 2359–2364.

[45] Wang, Qiang; Pan, Ya-Lin; Liang, Ren-Xiao; Hu, Yuan-Yuan;* Jia, Yi-Xia;* Synthesis of 3-Propargyl Isoindolinones by Pd/Cu-Catalyzed Enantioselective Heck/Sonogashira Reaction of Enamides, Org. Biomol. Chem. 2024, 23(5), 1073–1077.

[44] Wang, Qiang; Ruan, Zi-Sheng; Wang, Hong-Peng; Liang, Ren-Xiao; Hu, Yuan-Yuan;* Jia, Yi-Xia;* Cobalt-Catalyzed Intramolecular Enantioselective Reductive Heck Reaction toward the Synthesis of Chiral 3-Trifluoromethylated Oxindoles, J. Org. Chem. 2024, 89(23), 17133–17140.

[43] Wang, Bi; Liang, Ren-Xiao; Shen, Zhen-Lu;* Jia, Yi-Xia;* Copper-Catalyzed Intramolecular Dearomative aza-Wacker Reaction of Indole, Chem. Commun. 2024, 60(28), 3858–3861.

[42] Gao, Weiyang; Deng, Weichao; Gao, Yang; Liang, Renxiao; Jia, Yixia;* Intermolecular Enantioselective Dearomative Oxidative Heck Reaction of Indoles, Acta Chim. Sinica 2024, 82(1), 1–4.

[41] Lu, Jin-Bo; Xu, Xiao-Qiu; Ruan, Zi-Sheng; Liu, Kai; Liang, Ren-Xiao*; Jia, Yi-Xia*; Pd-Catalyzed Intramolecular Dearomative [4+2] Cycloaddition of Naphthalenes with Arylalkynes, Org. Lett. 2023, 25(45), 8139–8144.

[40] Liang, Ren-Xiao*; Tang, Heng-Wei; Liu, Jia-Liang; Xu, Jian-Feng; Chen, Ling-Jia; Jia, Yi-Xia*; Cobalt-Catalyzed Enantioselective Desymmetrizing Reductive Cyclization of Alkynyl Cyclodiketones, Chem. Sci. 2023, 14(23), 6393–6398.

[39] Hu, Yuan-Yuan; Xu, Xiao-Qiu; Deng, Wei-Chao; Liang, Ren-Xiao; Jia, Yi-Xia;* Nickel-Catalyzed Enantioselective Dearomative Heck-Reductive Allylic Defluorination Reaction of Indoles, Org. Lett. 2023, 25(33), 6122–6127.

[38] Lu, Jun; Li, Qichuang; Liang, Renxiao; Jia, Yixia;* Nickel-Catalyzed Intramolecular Dearomative Arylation of Pyridiniums and Quinoliniums, Chin. J. Org. Chem. 2023, 43(5), 1875–1882.

[37] Han, Xiao-Qing; Liu, Jing-Yuan; Lu, Jin-Bo; Liang, Ren-Xiao; Jia, Yi-Xia;* Dearomatizing [2+2+1] Spiroannulation of Indoles with Alkynes, Org. Lett. 2023, 25(1), 261–266.

[36] Liang, Ren-Xiao; Jia, Yi-Xia*; Aromatic π-Components for Enantioselective Heck Reactions and Heck/Anion-Capture Domino Sequences, Acc. Chem. Res. 2022, 55(5), 734–745.

[35] Liang, Ren-Xiao*; Chen, Jian-Fei; Huang, Ying-Ying; Yu, Ya-Ping; Zhang, Han-Yue; Song, Yu-Feng; Tsui, Gavin Chit*; Jia, Yi-Xia*; Enantioselective Pd-Catalyzed Dearomative Reductive Heck and Domino Heck–Suzuki Reactions of 2-CF₃-Indoles, Chem. Commun. 2022, 58(42), 6200–6203.

[34] Han, Xiao-Qing; Wang, Lei; Yang, Ping; Liu, Jing-Yuan; Xu, Wei-Yan; Zheng, Chao; Liang, Ren-Xiao; You, Shu-Li;* Zhang, Junliang;* Jia, Yi-Xia;* Enantioselective Dearomative Mizoroki-Heck Reaction of Naphthalenes, ACS Catal. 2022, 12(1), 655–661.

[33] Yang, Peng; Wang, Qiang; Cui, Bing-Hui; Zhang, Xiao-Dong; Liu, Hang; Zhang, Yue-Yuan; Liu, Jia-Liang; Huang, Wen-Yu; Liang, Ren-Xiao; Jia, Yi-Xia;* Enantioselective Dearomative [3+2] Umpolung Annulation of N-Heteroarenes with Alkynes, J. Am. Chem. Soc. 2022, 144(3), 1087–1093.

[32] Liang, Ren-Xiao; Song, Ling-Jie; Lu, Jin-Bo; Xu, Wei-Yan; Ding, Chao; Jia, Yi-Xia*; Palladium-Catalyzed Enantioselective Heteroarenyne Cycloisomerization Reaction, Angew. Chem. Int. Ed. 2021, 60(13), 7412–7417.

[31] Liang, Ren-Xiao; Zhong, Chao; Liu, Zhi-Hong; Yang, Miao; Tang, Heng-Wei; Chen, Jian-Fei; Yang, Yun-Fang*; Jia, Yi-Xia*; Enantioselective Arylation of Tetrasubstituted Enamines: Access to Enantioenriched Indolenine and 1H-Indole Derivatives, ACS Catal. 2021, 11(3), 1827–1832.

[30] Lu, Jun; Liang, Renxiao; Jia, Yixia;* Copper-Catalyzed Intramolecular Dearomative Arylation of Naphthylamines, Chin. J. Org. Chem. 2021, 41(10), 4007–4013.

[29] Xie, Jia-Qi; Liang, Ren-Xiao; Jia, Yi-Xia;* Recent Advances of Catalytic Enantioselective Heck Reactions and Reductive-Heck Reactions, Chin. J. Chem. 2021, 39(3), 710–728.

[28] Zhou, Bo; Liang, Renxiao; Cao, Zhongyan; Zhou, Pinghai; Jia, Yixia;* Palladium-Catalyzed Heck Reaction of Endocyclic Conjugated C=C Bonds of Pyrroles, Acta Chim. Sinica 2021, 79(2), 176–179.

[27] Zhu, Jiawen; Zhou, Bo; Cao, Zhongyan; Liang, Renxiao; Jia, Yixia;* Stereoselective 1,2-Dicarbofunctionalization of Trisubstituted Alkenes by Palladium-Catalyzed Heck/Suzuki or Heck/Sonogashira Domino Sequence, CCS Chem. 2021, 3(9), 36–45.

[26] Liang, Ren-Xiao; Chen, Ru-Yi; Zhong, Chao; Zhu, Jia-Wen; Cao, Zhong-Yan; Jia, Yi-Xia*; 3,3'-Disubstituted Oxindoles Formation via Copper-Catalyzed Arylboration and Arylsilylation of Alkenes, Org. Lett. 2020, 22(8), 3215–3218.

[25] Zhou, Bo; Wang, Hongliang; Cao, Zhong-Yan; Zhu, Jia-Wen; Liang, Ren-Xiao; Hong, Xin; Jia, Yi-Xia;* Dearomative 1,4-Difunctionalization of Naphthalenes via Palladium-Catalyzed Tandem Heck/Suzuki Coupling Reaction, Nat. Commun. 2020, 11(1), 4380.

[24] Liang, Ren-Xiao; Wang, Ke; Wu, Quan; Sheng, Wei-Jian; Jia, Yi-Xia*; Palladium-Catalyzed Dearomative Arylvinylation Reaction of Indoles with N‑Arylsulfonylhydrazones, Organometallics 2019, 38(20), 3927–3930.

[23] Liang, Ren-Xiao; Xu, Deng-Yun; Yang, Fu-Ming; Jia, Yi-Xia*; A Pd-Catalyzed Domino Larock Annulation/Dearomative Heck Reaction, Chem. Commun. 2019, 55(53), 7711–7714.

[22] Weng, Jian-Quan; Xing, Ling-Ling; Hou, Wen-Ren; Liang, Ren-Xiao*; Jia, Yi-Xia*; Palladium-Catalyzed Dearomative Arylphosphorylation of Indoles, Org. Chem. Front. 2019, 6(10), 3577–3580.

[21] Liang, Ren-Xiao; Wang, Ke; Song, Ling-Jie; Sheng, Wei-Jian; Jia, Yi-Xia*; Synthesis of Tetracyclic Indolin-3-ones through Pd-Catalyzed Intramolecular Deacetylative Dearomatization of 3-Acetoxy-indoles, RSC Adv. 2019, 9(25), 13959–13967.

[20] Qiu, Shaotong; Liang, Renxiao; Wang, Yongdong; Zhu, Shifa;* Domino Reaction between Nitrosoarenes and Ynenones for Catalyst-Free Preparation of Indanone-Fused Tetrahydroisoxazoles, Org. Lett. 2019, 21(7), 2126–2129.

[19] Li, Bao-Le; Gao, Wei-Yang; Li, Han; Zhang, Shuo-Qing; Han, Xiao-Qing; Lu, Jun; Liang, Ren-Xiao; Hong, Xin;* Jia, Yi-Xia;*Enantioselective Intramolecular Desymmetric α-Addition of Cyclohexanone to Propiolamide Catalyzed by Sodium L-Prolinate, Chin. J. Chem. 2019, 37(1), 63–70.

[18] Liang, Ren-Xiao; Yang, Run-Ze; Liu, Ren-Rong; Jia, Yi-Xia*; Palladium-Catalyzed Asymmetric Dearomative Alkenylation of Indoles through a Reductive-Heck Reaction, Org. Chem. Front. 2018, 5(11), 1840–1843.

[17] Li, Xiang; Zhou, Bo; Yang, Run-Ze; Yang, Fu-Ming; Liang, Ren-Xiao; Liu, Ren-Rong; Jia, Yi-Xia;* Palladium-Catalyzed Enantioselective Intramolecular Dearomative Heck Reaction, J. Am. Chem. Soc.2018, 140(42), 13945–13951.

[16] Luo, Hejiang; Liang, Renxiao; Chen, Lianfen; Jiang, Huanfeng; Zhu, Shifa;* A Silver-Catalyzed Three-Component Reaction via Stabilized Cation: Synthesis of Polysubstituted Tetrahydronaphthols and Tetrahydro-aphthylamines, Org. Chem. Front. 2018, 5(7), 1160–1164.

[15] Huang, Bing-Bing; Wu, Liang; Liu, Ren-Rong; Xing, Ling-Ling; Liang, Ren-Xiao; Jia, Yi-Xia;* Org. Chem. Front. 2018, 5(6), 929–932.

[14] Liang, Renxiao; Zhang, Jiantao; Chen, Lianfen; Zhu, Shifa;* Efficient Assembly of Tetracyclic Framework of Fluorenols through Silver-Catalyzed Tandem Reaction of Acceptor-Enynals and Alkynes via Unfavorable 6-endo-dig Cyclization, Asian J. Org. Chem. 2018, 7(3), 545–549.

[13] Liu, Ren-Rong; Liang, Ren-Xiao; Jia, Yi-Xia;* Construction of Benzylic Stereogenic Carbon Centers through Enantioselective Arylation Reactions, Synlett 2018, 29(2), 157–168.

[12] Liu, Ren-Rong; Wang, Yong-Gang; Li, Ying-Long; Huang, Bing-Bing; Liang, Ren-Xiao; Jia, Yi-Xia;* Enantioselective Dearomative Difunctionalization of Indoles by Palladium-Catalyzed Heck/Sonogashira Sequence, Angew. Chem. Int. Ed. 2017, 56(26), 7475–7478.

[11] Li, Baole; Liu, Renrong; Liang, Renxiao; Jia, Yixia;* Palladium/Amino Acid Co-Catalyzed Intramolecular α-Vinylationof Cyclohexanones, Acta Chim. Sinica 2017, 75(5), 448–452.

[10] Liu, Ren-Rong; Xu, Yang; Liang, Ren-Xiao; Xiang, Bin; Xie, Hu-Jun; Gao, Jian-Rong; Jia, Yi-Xia;* Spirooxindole Synthesis via Palladium-Catalyzed Dearomative Reductive-Heck Reaction, Org. Biomol. Chem. 2017, 15(13), 2711–2715.

[9] Ge, Chen; Liang, Ren-Xiao; Liu, Ren-Rong; Xiang, Bin; Jia, Yi-Xia;* Tetrahedron Lett. 2017, 58(2), 142–144.

[8] Liang, Renxiao; Chen, Kai; Zhang, Qiaohui; Zhang, Jiantao; Jiang, Huanfeng; Zhu, Shifa;* Rapid Access to 2-Methylene Tetrahydrofurans and γ-Lactones: A Tandem Four-Step Process, Angew. Chem. Int. Ed. 2016, 55(7), 2587–2591.

[7] Liang, Renxiao; Jiang, Huanfeng; Zhu, Shifa;* An Efficient Route to Highly Strained Cyclobutenes: Indium-Catalyzed Reactions of Enynals with Alkynes, Chem. Commun. 2015, 51(25), 5530–5533.

[6] Liang, Renxiao; Ma, Tongmei; Zhu, Shifa;* Silver-Catalyzed Reaction of Enynals with Alkenes: A Tandem 1,3-Dipolar Cycloaddition/Cyclopropanation, Org. Lett. 2014, 16(17), 4412–4415.

[5] Zhu, Shifa;* Liang, Renxiao; Jiang, Huanfeng; Wu, Wanqing; An Efficient Route to Polysubstituted Tetrahydronaphthols: Silver-Catalyzed [4+2] Cyclization of 2-Alkylbenzaldehydes and Alkenes, Angew. Chem. Int. Ed. 2012, 51(43), 10861–10865.

[4] Zhu, Shifa;* Liang, Renxiao; Jiang, Huanfeng; A Direct and Practical Approach for the Synthesis of N-Heterocyclic Carbene Coinage Metal Complexes, Tetrahedron 2012, 68(38), 7949–7955.

[3] Zhu, Shifa;* Liang, Renxiao; Chen, Lijuan; Wang, Chao; Ren, Yanwei; Jiang, Huanfeng; A Direct and Practical Approach for the Synthesis of Au(I)-NHC Complexes from Commercially Available Imidazolium Salts and Au(III) Salts, Tetrahedron Lett. 2012, 53(7), 815–818.

[2] Zhu, Shifa;* Chen, Lijuan; Wang, Chao; Liang, Renxiao; Wang, Xiujun; Ren, Yanwei; Jiang, Huanfeng; A Practical System to Synthesize the Multiple-Substituted 2,5-Dihydrofuran by the Intermolecular Dipolar Cycloaddition Reactions involving Acceptor/Acceptor-Substituted Diazo Reagents, Tetrahedron 2011, 67(30), 5507–5515.

[1] Zhu, Shifa;* Wang, Chao; Chen, Lijuan; Liang, Renxiao; Yu, Yingfeng; Jiang, Huanfeng; Modular Approach for Synthesis of Vicinal Diamines Containing Axial Chiral 1,1’-Binaphthyl from 1,2-Diaminoethane by Pd-Catalyzed N-Arylation Reactions, Org. Lett. 2011, 13(5), 1146–1149.

授权专利：

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[2] 一种含硼吲哚啉酮的制备方法，201911309561.9，2022.7.8

[1] 一种手性吲哚-2,3-并八元碳环化合物的制备方，202011448322.4，2022.11.4

* 指导或协助指导三十余名本科生完成毕业论文

* 作为第一或第二导师指导研究生二十余名

* 担任本科生2017级化工1701班、2021级化工2103班班主任

* 第一指导老师指导本科生参加第四届全国大学生化学实验创新设计大赛，获全国总决赛一等奖

(项目名称：钯-手性磷酸接力催化的一锅三步串联反应合成手性四氢喹啉；成员：钟哲、金张灵、史丽娟)