Jie Shen, Xinrui Zhang, Jie Wang, Xusheng Duan, junhao pan, Yue Cai, Bin Wei, Hong Wang, Xuanrong Sun*, Targeted Collagen Degradation by an MRI Probe Facilitates siRNA Delivery for Sequential Theranostics in Pulmonary Fibrosis, ACS Nano, 2025, accepted
Jie Shen; Xusheng Duan; Ting Xie; Xinrui Zhang; Yue Cai; Junhao Pan; Xin Zhang; Xuanrong Sun* ; Advances in Locally Administered Nucleic Acid Therapeutics, Bioactive Materials, 2025, 49:218-254
Yue Cai, Meilin Qiao, Xiuzhi Xie, Yujie Zhou, Ruibing Yu, Fuhang Song, Hong Wang, Huawei Zhang, Xuanrong Sun*, Intracellular MRSA-targeted lipid-polymer hybrid nanoparticles for macrophage reprogramming and intracellular MRSA eradication. Chemical Engineering Journal, 2025, 505:159665.
Yue Cai, Xinrui Zhang, Wentao Hu, Fuhang Song, Hong Wang, Huawei Zhang, Xuanrong Sun*, Enhancing transdermal delivery of chrysomycin A for the treatment of cutaneous melanoma and MRSA infections using Skin-Penetrating Peptide-Functionalized deformable liposomes. International Journal of Pharmaceutics. 2025, 670:125130.
Xuanrong Sun, Dehui Xie, Zhao Lou, Yujie Zhou, Ming Li, Qingyong Li, Yue Cai, T7 Peptide-modified macrophage membrane-coated nanoplatform for enhanced glima treatment. European Journal of Pharmaceutics and Biopharmaceutics. 2024, 204:114527
Ming Li, Xinrui Zhang, Yujie Zhou, Yuteng Chu, Jie Shen, Yue Cai, Xuanrong Sun*. Near Infrared-Activatable Biomimetic Nanoplatform for Tumor-Specific Drug Release, Penetration and Chemo-Photothermal Synergistic Therapy of Orthotopic Glioblastoma. International Journal of Nanomedicine. 2024, 11:19:6999-7014
Xuanrong Sun*, Tenghan Zhang, Zhao Lou, Yujie Zhou, Yuteng Chu, Dongfang Zhou, Juhong Zhu, Yue Cai, Jie Shen*. A size shrinkable dendrimer-lipid hybrid nanoassembly for reversing tumor drug resistance. Green Chemical Engineering. 2024, 6(1):116-125.
Xuanrong Sun; Yubei Gong; Ting Xie; Zixi Fu; Dongze Lu; Bin Wei; Yue Cai; Wenlong Yao; Jie Shen; Nanoscale Liposomes Co-Loaded with Irinotecan Hydrochloride and Thalidomide for Colorectal Cancer Synergistic Therapy, Macromolecular Bioscience, 2024, 2400478
Wan, Qianyu, Sun Yuji, Sun Xuanrong*, Zhou Zhuxian*. Rational design of polymer-based mRNA delivery systems for cancer treatment. Polymer Chemistry. 2024, in press.
Jingyi Lu, Xiaoling Xu, Xuanrong Sun*, Yongzhong Du*, Protein and Peptide-Based Renal Targeted Drug Delivery Systems, Journal of Controlled Release. 2024, 366: 65-84
Qiwen shi, Mengxia Lin, Xiang Cheng, Ziyuan Zhang, Shufen Deng, Ke Lang, Zhikun Yang, Xuanrong Sun#. KPNB1-mediated nuclear import in cancer. European Journal of Pharmacology, 2023, 15;955:175925
Yue Cai, Yuteng Chu, Yubei Gong, Yulu Hong, Fuhang Song, Hong Wang, Huawei Zhang, Xuanrong Sun#. Enhanced Transdermal Peptide-Modified Flexible Liposomes for Efficient Percutaneous Delivery of Chrysomycin A to Treat Subcutaneous Melanoma and Intradermal MRSA Infection. Advanced Healthcare Materials, 2023, 12(26):e2300881
Qianyu Wan, Xinrui Zhang, Dongfang Zhou, Rui Xie, Yue Cai, Kehao Zhang, Xuanrong Sun#, Inhaled nano-based therapeutics for pulmonary fibrosis: recent advances and future prospects. Journal of Nanobiotechnology, 2023, 21(1):215.
Feihu Wang, Hao Su, Zeyu Wang, Caleb F. Anderson, Xuanrong Sun, Han Wang, Philippe Laffont, Justine Hanes*, Honggang Cui*, Supramolecular Filament Hydrogel as a Universal Immunomodulator Carrier for Immunotherapy Combinations, ACS Nano, 2023,17,11,10651-10664.
Zhikun Yang, Yue Cai, Xue Yang, Xuanrong Sun# et al. Novel Benzo Five-Membered Heterocycle Derivatives as P-Glycoprotein Inhibitors: Design, Synthesis, Molecular Docking, and Anti-Multidrug Resistance Activity[J]. J. Med. Chem. 2023, 66, 8, 5550–5566.
Zhikun Yang, Xue Yang, Yasheng Li, Yue Cai, Yanlei Yu, Wenya Zhuang, Xuanrong Sun et al. Discovery of 2,5-disubstituted furan derivatives featuring a benzamide motif for overcoming P-glycoprotein mediated multidrug resistance in MCF-7/ADR cell[J]. European Journal of Medicinal Chemistry, 2023, 257, 5, 115462.
郑珊珊,蔡悦,龚瑜贝,洪煜璐,孙漩嵘*,纳米载体用于包载生物活性多肽的研究,中国生物医学工程学报,2023,42,1
Wang Yi, Wang Wenchao, Yu Endian, Zhuang Wenya, Sun Xuanrong, Wang Hong, Li Qingyong, Preparation of a camptothecin analog FLQY2 self-micelle solid dispersion with improved solubility and ADME properties, Journal of Nanobiotechnology, 2022, 5; 20(1):402
Wang Yi, Zhang Xiangli, Zhuang Wenya, Yu Yanlei, Sun Xuanrong, Wang Hong, Li Fengzhi, Li Qingyong, Investigation of the Uptake and Transport of Two Novel Camptothecin Derivatives in Caco-2 Cell Monolayers, Molecules, 2022, 27, 12.
Chen Yan, Liu Pengfu, Wu Jiequn, Yan Wanqing,Xie Saixue, Sun Xuanrong, Ye Bangce, Chu Xiaohe, N-acylhomoserine lactonase-based hybrid nanoflowers: a novel and practical strategy to control plant bacterial diseases, Journal of Nanobiotechnology, 2022, 20, 1
Mengxue Wei, Si-si Zhang, Xuanrong Sun, Yang Ji, Pei-wen Yang, Xue-Qiang Li,Design, Synthesis, and Biological Evaluation of Artemisinin-Piperazine-Phosphoramide Mustard Hybrids as Potential Anticancer Agents. ChemMed Chem. 2022, accepted.
Mengxue Wei, Yixuan Zhou, Mengxia Lin, Jun Zhang, Xuanrong Sun*, Design, synthesis and biological evaluation of rhein-piperazine-dithiocarbamate hybrids as potential anticancer agents. European Journal of Medicinal Chemistry. 2022, 241(5), 114651
Haohua Liu, Yue Cai, Yuteng Chu, Xiaojie Yu, Fuhang Song, Hong Wang, Huawei Zhang, Xuanrong Sun*, Formulation of Chrysomycin A Cream for the Treatment of Skin Infections,Molecules 2022, 27, 4613.
Shanshan Zheng, Yue Cai, Yubei Gong, Yulu Hong, Licheng Gao, Le Li, Xuanrong Sun*, Legumain/pH Dual-Responsive Lytic Peptide-Paclitaxel Conjugate for Synergistic Cancer Therapy, Drug Delivery, 2022, 29:1, 1764-1775
Dabu Zhu, Qiuqin Zhang, Yifang Chen, Minghua Xie, Jianbo Li, Shen Yao, Ming Li, Zhao Lou, Yue Cai, Xuanrong Sun*, Mechanochemical preparation of triptolide-loaded self-micelle solid dispersion with enhanced oral bioavailability and improved anti-tumor activity, Drug Delivery. 2022, 29:1,1398-1408
龚喻贝,李少广,洪煜璐,谢德晖,郑珊珊,孙漩嵘*,应用纳米技术调控微生物组治疗癌症的研究进展,药学学报,2022,57(4):952-962
Feihu Wang, Hao Su, Dongqing Xu, Maya K. Monroe, Caleb F.Anderson, Weijie Zhang, Richard Oh, Zongyuan Wang, Xuanrong Sun, Han Wang, Fengyi Wan, Honggang Cui. Therapeutic supramolecular tubustecan hydrogel combined with checkpoint inhibitor elicits immunity to combat cancer. Biomaterials. 2021,279
Zhuomin Xu, Shanshan Zheng, Xin Gao, Yulu Hong, Yue Cai, Qiuqin Zhang, Jiani Xiang, Dehui Xie, Fuxing Song, Huawei Zhang, Hong Wang and Xuanrong Sun*, Mechanochemical preparation of chrysomycin A self-micelle solid dispersion with improved solubility and enhanced oral bioavailability. Journal of Nanobiotechnology, 19:164, 2021
Xuanrong Sun*, Yulu Hong, Yubei Gong, Shanshan Zheng and Dehui Xie, Bioengineered Ferritin Nanocarriers for Cancer Therapy. International Journal of Molecular Sciences, 22,7023, 2021
Xuanrong Sun, Tianwei Zhang , Yue Cai, Ke Yang, Tingting Peng, Renhao Liu and Xing-Nuo Li, Tonkinensine B induces apoptosis through mitochondrial dysfunction and inactivation of the pI3K/Akt pathway in triple-negative breast cancer cells. Journal of Pharmacy and Pharmacology, 73, 10, 1397-1404, 2021.
Liu Renhao, Bao Xiaoze, Sun Xuanrong, Cai Yue, Zhang Tianwei, Ye Xinyi, Li Xingnuo, Cytisine-flavonoid conjugates: Synthesis and antitumor structure-activity relationship research, Tetrahedron Letters, 2020, 61, 17.
Qi Shuai, Yue Cai, Guangkuo Zhao, Xuanrong Sun*, Cell-penetrating peptide modified PEG-PLA micelles for efficient PTX delivery. International Journal of Molecular Sciences, 21(1856), 2020
Yue Cai, Zhuomin Xu, Qi Shuai, Fangtao Zhu, Jiao Xu, Xin Gao, Xuanrong Sun*, Tumor-targeting peptide functionalized PEG-PLA micelles for efficient drug delivery. Biomaterial Science, 15;8:2274-2282, 2020.
Wang, F.; Xu, D.; Su, H.; Zhang, W.; Sun, X.; Monroe, M.; Chakroun, R.W.; Wang, Z.; Dai, W.; Oh, R.; Wang, H.; Wan, F.; Cui, H., Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker-based immunotherapy. Science Advances, 6(18):eaaz8985, 2020.
孙漩嵘,徐卓敏,蔡悦,微流控技术在纳米药物载体制备中的应用,中国药学杂志,55(8), 2020.
Xuanrong Sun*, Yue Cai, Zhuomin Xu and Dabu Zhu,Preparation and Properties of Tumor-Targeting MRI Contrast Agent Based on Linear Polylysine Derivatives. Molecules, 24(1477), 2019.
Xuanrong Sun*, Dabu Zhu, Yue Cai, Guobang Shi, Mengshi Gao, Minzi Zheng. One-step mechanochemical preparation and prominent antitumor activity of SN-38 self-micelle solid dispersion. International journal of nanomedicine, 14(2115-2126), 2019.
Xuanrong Sun*, Longchao Zhang*, Mengshi Gao, Xiangjie Que, Chenfeng Zhou, Dabu Zhu and Yue Cai. Nanoformulation of a Novel Pyrano[2,3-c] Pyrazole Heterocyclic Compound AMDPC Exhibits Anti-Cancer Activity via Blocking the Cell Cycle through a P53-Independent Pathway. Molecules, 24(624), 2019.
Xinglu Huang, Jie Zhuang, Seung Woo Chung, Buwei Huang, Gilad Halpert, Karina Negron, Xuanrong Sun, Jun Yang, Yumin Oh, Paul M. Hwang, Justin Hanes and Jung Soo Suk. Hypoxia-tropic Protein Nanocages for Modulation of Tumor- and Chemotherapy-Associated Hypoxia. ACS Nano,13,236-247, 2019.
Ting-Ting Peng, Xuanrong Sun, Ren-Hao Liu, Lu-Xia Hua, Dong-Ping Cheng, Bin Mao and Xing-Nuo Li. Cytisine-Pterocarpan Derived Compounds: Biomimetic Synthesis and Apoptosis-Inducing Activity in Human Breast Cancer Cells. Molecules, 23(3059), 2018.
Xuanrong Sun*, Guowei Wang*, Hao Zhang, Shiqi Hu, Xin Liu, Jianbin Tang and Youqing Shen. The Blood Clearance Kinetics and Pathway of polymeric micelles in cancer drug delivery. Acs Nano, 12(6), 6179-6192, 2018.
Xuanrong Sun, Dabu Zhu, Yue Cai, Macrophages Mediated Biomimetic Drug Delivery Systems, Journal of nanomedicine, 1(1), 2018.
Zhangdan Huang*, Xuanrong Sun*, Xuanrong Sun, Xiangrui Liu, Youqing Shen, Kai Wang. Macrophages as an active tumor-targeting carrier of SN38-nanoparticles for cancer therapy. Journal of drug targeting, 26(5-6), 458-465, 2018.
高梦诗,郑敏子,叶心怡,施国邦,阙祥洁,张隆超,孙漩嵘*。一种新型二氢吡喃并[2,3-c]吡唑类衍生物的体外抑瘤作用及机制,中国药理学与毒理学杂志,32(8),614-620,2018。
孙漩嵘,张隆超,施绮雯,李汉兵,赵航。细胞−纳米药物递送系统的研究进展,药学学报,52(7),1110-1116,2017。
Xuanrong Sun, Longchao Zhang, Macrophage-mediated delivery of microparticles into tumor hypoxia zones. Journal of Controlled Release, 259,e159, 2017.
Xiaoman Mao, Jingxing Si, Qian Huang, Xuanrong Sun, Qianzhi Zhang, Youqing Shen, Jianbin Tang, Xiangrui Liu, Meihua Sui. Self-Assembling Doxorubicin Prodrug Forming Nanoparticles and Effectively Reversing Drug Resistance In Vitro and In Vivo. Advanced Healthcare Materials, 5, 2517-2527, 2016.
Xuanrong Sun, Shao Shiqun, Shen Youqing, Cascade-released Nanoassembly for Cancer Drug Delivery. Nanomedicine, 12(2):471-472, 2016.
Xumeng Wu*, Xuanrong Sun*, Zhiqian Guo, Jianbin Tang, Youqing Shen, Tony D James, He Tian, Weihong Zhu, In Vivo and In Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug. Journal of the American Chemical Society, 136(9), 2579-2588, 2014.
Qihang Sun*, Xuanrong Sun*, Xinpeng Ma, Zhuxian Zhou, Erlei Jin, Bo Zhang, Youqing Shen, Edward A Van Kirk, William J Murdoch, Joseph R. Lott, Timothy P. Lodge, Maciej Radosz and Yuliang Zhao, Integration of Nanoassembly Functions for an Effective Delivery Cascade for Cancer Drugs. Advanced Materials, 26(45):7615-21, 2014.
Jingqiang Wang*, Xuanrong Sun*, Meihua Sui, Jianbin Tang, Youqing Shen. Tumor Redox Heterogeneity-Responsive Prodrug Nanocapsules for Cancer Chemotherapy. Advanced Materials, 25, 3670-3676, 2013.
Xumeng Wu*, Shu Chang*, Xuanrong Sun*, Zhiqian Guo, Yongsheng Li, Jianbin Tang, Youqing Shen, Jianlin Shi, He Tian, Weihong Zhu, Constructing Near-infrared Silica-Cyanine Hybrid Nanocomposite for in vivo Bioimaging: A Breakthrough in Photo-Stability and Bright Fluorescence with Large Stokes Shift of Cyanine via Encapsulation. Chemical Science, 4, 1221-1228, 2013.
Xuanrong Sun, Hui Lu, Yuanying Jiang, Yingying Cao, CaIPF19998 Reduces Drug Susceptibility by Enhancing the Ability of Biofilm Formation and Regulating Redox Homeostasis in Candida albicans. Current Microbiology, 67, 322-326, 2013.
Xuanrong Sun, Zhongchun Chen, Meihua Sui, Jianbin Tang and Youqing Shen. Parallel Synthesis of Polymers from Epoxy-Amine Reaction for Gene Delivery. 2012 Symposium on Innovative Polymers for Controlled Delivery. Journal of Controlled Release, 172, e118, 2012.
Jun Yang, Xuanrong Sun, Weiwei Mao, Meihua Sui, Jianbin Tang and Youqing Shen. Conjugate of Pt (IV)-Histone Deacetylase Inhibitor as Prodrug for Cancer Chemotherapy. Molecular pharmaceutics, 9(10), 2793-2800,2012.
Kedong Lu, Mingzhuo Cao, Weiwei Mao, Xuanrong Sun, Jianbin Tang, Youqing Shen and Meihua Sui. Targeted Acid-labile Conjugates of Norcantharidin for Cancer Chemotherapy. Journal of Materials Chemistry, 22, 15804-15811, 2012.
Erlei Jin, Bo Zhang, Xuanrong Sun, Zhuxian Zhou, Xinpeng Ma,Qihang Sun, Jianbin Tang, Youqing Shen, Edward A Van Kirk,William J Murdoch, Maciej Radosz, Acid Active Cell-Penetrating Peptides for In Vivo Tumor-Targeted Drug Delivery.,Journal of the American Chemical Society, 135, 933-940, 2012.
Hui Lu, ZhenYu Zhu, LingLing Dong, XinMing Jia, Xuanrong Sun, Lan Yan, YiFeng Chai, YuanYing Jiang, YingYing Cao. Lack of trehalose accelerates H2O2-induced Candida albicans apoptosis through regulating Ca2+ signaling pathway and caspase activity. Plos One, 6(1), e15808, 2011.
Shan Huang, Ying Ying Cao, Bao Di Dai, Xuanrong Sun, Zhen Yu Zhu, Yong Bing Cao, Yan Wang, Ping Hui Gao, Yuan Ying Jiang, In Vitro Synergism of Fluconazole and Baicalein against Clinical Isolates of Candida albicans Resistant to Fluconazole. Biological and Pharmaceutical Bulletin, 31(12), 2234-6, 2008.
1. 一种增强金黄霉素A水溶性的组合物及其制备与应用,专利号:202110326317.4
2. 一种抗癌药物组合物,证书号440551