王龑

王龑，教授，博士生导师，浙江省首批高校领军人才青年优秀人才，浙江工业大学“十四五”高层次人才培养计划（D类）、青年英才支持计划（优青）。从事真菌毒素等食品危害因子的生成机制与控制技术、农产品贮藏保鲜与食品非热杀菌新技术、食品分子毒理与营养代谢研究。主持国家自然科学基金面上项目、青年项目，国家重点研发计划子课题、浙江省重点研发项目子课题等省部级以上课题10项，横向课题3项，作为中方负责人主持科技部高端外国专家项目。发表学术论文90余篇，授权国家发明专利20余项，参编著作3部，主编教材1部、副主编3部，省部级一等奖1项（8/14）。

2018年至今，浙江工业大学食品科学与工程学院

2025-2026年新西兰奥克兰大学访问学者

2022-2023年江南大学国内高校访问学者

2016-2017年美国内布拉斯大学林肯分校访问学者

2013-2018年中国农业科学院农产品加工研究所

2013年博士毕业于中国农业大学食品科学与营养工程学院

1. 国家自然科学基金面上项目“脉冲强光技术对赭曲霉毒素A的消减与控制机制研究”，2024-2027，主持

2. 浙江省属高校基本科研业务费青年科学家专项“真菌毒素消减脱除及肝肾毒性的营养干预研究，2025-2027，主持

3. 浙江省重点研发项目“出口农产品真菌毒素风险识别、监测及其控制技术研发”，2021-2023，课题主持

4. 科技部国家外国专家项目“食品中产毒真菌多样性、产毒真菌检测与预警技术研究”，2020，主持

5. 开放课题“恰玛古类黄酮提取鉴定及高尿酸血症缓解机制研究”，2025-2027，主持

6. 企业项目“千里飘香发酵食品研发”，2022-2024，主持

7. 企业项目“腌渍脆梅生产工艺改进及应用”，2021-2023，主持

8. 企业项目“珍珠主要功能成分分离、结构解析及系列产品深度开发研究”，2021-2022，主持

9. 国家重点研发专项“食品中生物源危害物阻控技术及其安全性评价”子课题” ，2017-2021，主持

10. 国家自然科学基金青年项目，2017-2019，主持

11. 科技部重大专项“转基因生物的食用和饲用安全性评价”，2016-2020，骨干参加

12. 科技部973计划项目，2013-2017，骨干参加

13. 北京市自然科学基金青年项目，2015-2016，主持

1. Yan Wang*, Jiayu Xu, Sifan Lu, Jing Neng, Hao Yan*, Antonio F. Logrieco. Chitosan-ε-polylysine‑sodium tripolyphosphate based Pickering emulsions for co-encapsulation of cinnamaldehyde and linalool: An effective sustained-release system against toxigenic fungi. Food Chemistry, 2026, 147838. https://doi.org/10.1016/j.foodchem.2025.147838

2. Tosin  Victor Adegoke, Sifan Lu, Ogedegbe Gloria Adegoke, Yufei Wang, Yan Wang*. Optimizing single and cascade microbial enzyme systems through site-directed mutagenesis for enhancing mycotoxin detoxification. Biotechnology Advances, 2025, 87, 108751. https://doi.org/10.1016/j.biotechadv.2025.108751

3. Jingying Pei, Yufei Wang, Yuhang Hu,Peilong Sun, Yan Wang*. Effect of water-soluble antimicrobial films of carboxymethyl chitosan containing pearl powder and Tremella fuciformis polysaccharides on strawberry fresh-keeping. International Journal of Biological Macromolecules, 2025, 330(4), 148262. https://doi.org/10.1016/j.ijbiomac.2025.148262

4. Jingying Pei, Yufei Wang,Qing Zhang, Jiahao Yu, Peilong Sun, Yan Wang*. A water-soluble antibacterial films of gelatin/carboxymethyl cellulose sodium incorporated with Grifola frondosa polysaccharides and pearl powder for fruit preservation. International Journal of Biological Macromolecules, 2025, 311(2):  143704. https://doi.org/10.1016/j.ijbiomac.2025.143704

5. Yufei Wang, Qing Zhang, Jingying Pei, Yijia Su, Tosin Victor Adegoke, Yan Wang*. Rational screening of four peroxidases with high aflatoxin B1 degradation efficiency via integrated computational simulations. Journal of Agricultural and Food Chemistry, 2025, 73(38), 24354-24368. 10.1021/acs.jafc.5c04916 Cover

6. Aiyun Zhou, Qing Zhang, Tosin Victor Adegoke, Dongyuan Chen, Jing Neng, Yan Wang*. Pulsed light inhibits aflatoxins production of Aspergillus flavus, degrades aflatoxin B1 and its potential mechanisms. Food Chemistry, 2025, 492, 145655. https://doi.org/10.1016/j.foodchem.2025.145655

7. Sifan Lu, Jiayu Xu, Aiyun Zhou, Jian Wang, Yan Wang*. Fabrication, characterization, and photodynamic inactivation activity of cinnamaldehyde-curcumin loaded Pickering emulsions on foodborne pathogenic microorganisms. Food Chemistry, 2025, 490, 145158. https://doi.org/10.1016/j.foodchem.2025.145158

8. Yu Zou, YuhengYang, Jingying Pei, Peilong Sun, Yan Wang*. Ganoderma lucidum polysaccharide/carboxymethyl chitosan hydrogels modulate macrophage polarization for wound healing. Biomacromolecules, 2025, 26(4): 2675-2689. https://doi.org/10.1021/acs.biomac.5c00112 Cover

9. Xueying Gao, Jie Shang, Minghao Zhang, Hao Yan*, Kai Yang, Yan Wang*. Mechanisms underlying the antimicrobial effects of cold plasma on Kazachstania bulderi in bayberry juice through transcriptomic analysis. LWT-Food Science and Technology, 2025, 222, 117336. https://doi.org/10.1016/j.lwt.2025.117336 

10. Yan Wang, Xifan Yu, Wei Li, Bei Yu, Aiyun Zhou, Hao Yan*, Peilong Sun*. The variations analysis of volatile flavors and microbial communities during fermentation of Chinese Taizhou pickle, and the isolation and identification of fermentative microorganisms. LWT-Food Science and Technology, 2025, 216, 117331.  https://doi.org/10.1016/j.lwt.2025.117331 

11. Yan Wang*, Aiyun Zhou, Bei Yu, Xiulan Sun*. Recent advances in non-contact food processing technologies for the decontamination of fungi and mycotoxins. Foods, 2024, 13(14): 2244. DOI10.3390/foods13142244. 

12. Yufei Wang, Fei Liu, Jingying Pei, Hao Yan*, Yan Wang*. The AwHog1 transcription factor influences the osmotic stress response, mycelium growth, OTA production, and pathogenicity in Aspergillus westerdijkiae fc-1. Toxins, 2023, 15(7), 432. https://doi.org/10.3390/toxins15070432. 

13. Yan Wang*, Yong Zheng, Aiyun Zhou, Jing Neng, Di Wu, Xiao Li Shen, Xiuyu Lou*, Kai Yang* Transcriptomic analysis reveals the inhibition mechanism of pulsed light on fungal growth and ochratoxin A biosynthesis in Aspergillus carbonarius. Food Research International, 2023, 165, 112501. https://doi.org/10.1016/j.foodres.2023.112501.

14. Yan Wang, Yong Zheng, Jie Shang, Di Wu, Aiyun Zhou, Ming Cai, Haiyan Gao, Kai Yang* Pulsed light reduces postharvest losses of Chinese bayberries during cold storage by affecting fungal community. Food Control, 2023, 146, 109524. doi.org/10.1016/j.foodcont.2022.109524

15. Yue Guan, Junning Ma, Jing Neng, Bolei Yang, Yan Wang*, Fuguo Xing*. A novel and label-free chemiluminescence detection of zearalenone based on a truncated aptamer conjugated with a G-quadruplex DNAzyme. Biosensors, 2023, 13(1), 118.  https://doi.org/10.3390/bios13010118 . 

16. Yan Wang, Jiayu Xu, Wei Lin, Jian Wang, Hao Yan*, Peilong Sun*. Citral and cinnamaldehyde - Pickering emulsion stabilized by zein coupled with chitosan against Aspergillus spp. and their application in food storage. Food Chemistry, 2023, 403, 134272. doi.org/10.1016/j.foodchem.2022.134272

17. Yan Wang*, Jie Shang, Ming Cai, Yang Liu*, Kai Yang* Detoxification of mycotoxins in agro-products and foods by non-thermal physical technologiy: A Review of the Past Five Decades. Critical Reviews in Food Science and Nutrition, 2022, DOI: 10.1080/10408398.2022.2095554 

18. Yan Wang, Wei Lin, et al. iTRAQ proteome analysis of the inhibitory effects of citral on Aspergillus ochraceus. Journal of the Science of Food and Agriculture, 2021, 101(12), doi: 10.1002/jsfa.11140. 

19. Yan Wang, Yue Guan, et al. Quantitative proteomic profiling of fungal growth, development and ochratoxin A production in Aspergillus ochraceus on high- and low-NaCl cultures. Toxins, 2021, 13, 51. doi.org/10.3390/toxins13010051.

20. Jingying Pei†, Yan Wang†, et al. Extraction, purification, bioactivities and application of matrix proteins from pearl powder and nacre powder: A review. Frontiers in Bioengineering and Biotechnology, 2021, 292(9), doi: 10.3389/fbioe.2021.649665. 

21. Yan Wang, Hao Yan*, et al. The influence of NaCl and glucose content on growth and ochratoxin A production by Aspergillus ochraceus, Aspergillus carbonarius and Penicillium nordicum. Toxins, 2020, 12, 515. doi:10.3390/toxins12080515.

22. Yan Wang, Hao Yan, Qi Wang, Ran Zheng, Kai Xia*, Yang Liu*. Regulation of the phytotoxic response of Arabidopsis thaliana to the Fusarium mycotoxin deoxynivalenol. Journal of Integrative Agriculture 2020, 19(3): 759-767.

23. Yan Wang, Liuqing Wang, et al. A Consensus Ochratoxin A Biosynthetic Pathway: Insights from the Genome Sequence of Aspergillus ochraceus and a Comparative Genomic Analysis. Applied and Environmental Microbiology, 2018, DOI: 10.1128/AEM.01009-18.

24. Yan Wang, Fei Liu, et al. pH-Signaling transcription factor AopacC regulates Ochratoxin A biosynthesis in Aspergillus ochraceus. Journal of Agricultural and Food Chemistry, 2018, 66(17): 4394-4401. 

25. Yan Wang, Weiwei Zhao, et al. Changes in glutathione biosynthesis and metabolism to Ochratoxin A stress in Arabidopsis thaliana. Plant Physiology and Biochemistry, 2014,79: 10-18. 

26. Yan Wang, Junran Hao, Weiwei Zhao, Zhuojun Yang, Weihong Wu, Yu Zhang, Wentao Xu*, Yunbo Luo, Kunlun Huang*. Comparative proteomics analysis reveals dynamic regulatory mechanisms in response to ochratoxin A stimulus in Arabidopsis thaliana seedlings. Plant Molecular Biology, 2013, 82: 321-337. 

27. Yan Wang, Wentao Xu, Weiwei Zhao, et al. Comparative analysis of the proteomic and nutritional composition of transgenic rice seeds with Cry1ab/ac genes and their non-transgenic counterparts. Journal of Cereal Science, 2012, 55, 226-233. 

28. Yan Wang, Xiaoli Peng, Wentao Xu*, Yunbo Luo, Weiwei Zhao, Junran Hao, Zhihong Liang, Yu Zhang, Kunlun Huang*. Transcript and protein profiling analysis of OTA-induced cell death reveals the regulation of the toxicity response process in Arabidopsis thaliana. Journal of Experimental Botany, 2011, 63 (5): 2171-2187.

    
    

主讲本科生必修课《食品微生物检验学》、《食品分析实验》，研究生国际化课程《天然产物的发现与食品新资源开发》，博士研究生专业选修课《食品酶工程》

主持浙江省高等教育“十四五”教学改革项目（2023-2024），校级创新性实验项目（2019-2021），校研究生教学改革项目（2026-2027）

主编教材《食品微生物检验学》（中国轻工业出版社，2025）

副主编教材《食品安全学》（科学出版社，2024）、《现代食品分析实验指导》（化学工业出版社，2024）、《食品分析与安全检测技术》（中国原子能出版社，2020）

1. 浙江工业大学2024年度优秀教师

2. 浙江工业大学2024年度优秀本科生导师

3. 浙江工业大学2022届本科毕业论文（设计）优秀指导教师

4. 浙江工业大学2020年度优秀班主任

5. 指导研究生获得浙江省专业学位研究生优秀实践成果2项、浙江工业大学优秀硕士学位论文1篇

6. 指导本科生参加浙江省大学生科技创新活动（新苗计划）、浙江省大学生创新训练计划项目、运河杯等，获得省级、校级立项，第八届全国大学生生命科学竞赛（创新创业类）二等奖、“欧倍尔杯”第五届全国食品专业工程实践训练综合能力竞赛（南部赛区）一等奖、浙江工业大学“大学生节能减排社会实践与科技竞赛”二等奖、农夫山泉杯在杭高校食品科技创新大赛一等奖

国家自然基金评审专家，中华预防医学会食品卫生分会青年委员、国家真菌毒素科技创新联盟理事，生物毒素研究青年学术委员会委员，American Chemical Society (ACS)会员、中国食品科学技术学会高级会员、中国菌物学会会员、浙江省食品学会会员、浙江菌物学会会员，核农学报、Journal of Future Foods期刊青年编委，Crit Rev Food Sci, Food Chem, JAFC, TIFS，Food Control, Phytomedicine, Environmental Pollution，Food Microbiology，LWT，Mycotoxin Research，Food and Chemical Toxicology，Food Bioscience，FHSW，Frontiers，eFOOD等20余个期刊审稿人