薛斌

薛斌，博士，山西文水人，2020年毕业于天津科技大学，2020-2022在天津科技大学从事博士后研究，2023年入选浙江工业大学“青年英才”计划，2024年入选浙江工业大学“十四五高层次D类人才”培育计划。主要从事酶分子改造、生物催化与酶的高效表达。目前主持浙江省“尖兵”科技计划项目课题1项，浙江省高校基本科研业务费项目1项，国家自然科学基金青年项目1项和中国博士后科学基金面上项目1项。在PNAS、eLife和J Cell Biol等知名期刊发表论文10篇，申请中国发明专利4项。

1. 浙江省“尖兵”科技计划项目，2025C01121, 微生物细胞工厂的智能设计与工业应用, 2025/01-2026/12, 课题负责人

2. 浙江省高校基本科研业务费项目，RF-A20240541, 工程化枯草芽孢杆菌底盘菌株生产蛋白质和高价值医药化学品, 2025-01-01-2027-12-31，项目负责人

3. 中国博士后科学基金,2021M692403, LZTFL1通过BBSome调控纤毛内号蛋白蛋白定位的研究，2021.01-2022.12, 8万元,  结题,  主持

4. 国家自然科学基金青年科学基金项目,32100541,LZTFL1调控BBSome 纤毛内运输的分子机制研究, 2022.01-2024.12, 30万元,  结题,  主持

1. Bin Xue; Yang-Yang Li; Bei-Feng-Chu Zheng; Chan Zhang; Hadiatullah Hadiatullah; Wen-Ting Dai; Ya-Jun Wang; Zhen-Chuan Fan*. Expression and Characterization of Recombinant Triple Laterosporulin in Chlamydomonas reinhardtii, Probiotics. Antimicro., 2025. https://doi.org/10.1007/s12602-025-10523-4

2.Bin Xue#; Yan-Xia Liu#; Bin Dong; Jenna L. Wingfield; Mingfu Wu;   Jun Sun; Karl F. Lechtreck; Zhen-Chuan Fan*. Intraflagellar transport protein RABL5/IFT22 recruits the BBSome to the basal body through the GTPase ARL6/BBS3, Proc Natl AcadSci U S A, 2020, 117(5): 2496-2505.

3.Wei-Yue Sun#, Bin Xue#, Yan-Xia Liu#, Rui-Kai Zhang , Rong-Chao Li, Wen Xin, Mingfu Wu, Zhen-ChuanFan*. Chlamydomonas LZTFL1 mediates phototaxis via controlling BBSome recruitment to the basal body and its reassembly at the ciliary tip. Proc Natl AcadSci U S A, 2021, 118(35): e2101590118.

4.Yan-Xia Liu#; Bin Xue#; Wei-Yue Sun; Jenna L Wingfield; Jun Sun; Mingfu Wu; Karl F Lechtreck; Zhelong Wu; Zhen-Chuan Fan*. Bardet-Biedl syndrome 3 protein promotes ciliary exit of the signaling protein phospholipase D via the BBSome, eLife, 2021, 10:e59119. 

5.Bin Xue#; Chun-Ming Dong; He-He Hu; Bin Dong; Zhen-Chuan Fan*; Chlamydomonasreinhardtii-expressed Multimer of ToAMP4 Inhibits the Growth of Bacteria of both Gram-positive and Gram-negative, Process Biochemsitry, 2020, 91: 311-318.

6.Yan-Xia Liu, Wei-Yue Sun, Bin Xue, Rui-Kai Zhang, Wen-Juan Li, XixianXie and Zhen-Chuan Fan*. ARL3 Mediates BBSomeCiliary Turnover by Promoting Its Outward Movement Across the Transition Zone, J Cell Biol, 2022, 221(10): e202111076.

7.Jin Dai, Gui Zhang, Rama A. Alkhofash, BetlehemMekonnen, SahanaSaravanan, Bin Xue, Zhen-Chuan Fan, EwelinaBetlina, Douglas G Cole, Peiwei Liu and Karl Lechtreck*. Loss of ARL13 impedes BBSome-dependent cargo export from Chlamydomonascilia, J Cell Biol, 2022, 221(10):e202201050.