原攀红

简介

       主要从事 合成生物学 和 酶工程 研究。在《ACS Synthesis Biology》、《Carbohydrate Polymers》、《Enzyme And Microbial Technology》、《Critical Reviews in Biotechnology》、《Applied Microbiology And Biotechnology》等期刊上发表科研论文数篇。目前，授权发明专利多件，主持基金项目多项。

2025年招收研究生，微信和手机同号18058747894，邮箱yph@zjut.edu.cn

科研专著  

1.  Panhong Yuan; Shixiu Cui; Jianghua Li; Guocheng Du; Jian Chen; Long Liu; In Systems and Synthetic Biotechnology for Production of Nutraceuticals, Springer-Nature, 2019,ISBN: 978-981-15-0445-7. 发表

代表性科研论文

1.  Panhong Yuan; Ziyan Chen; Mengtao Xu; Wenfeng Cai; Zhizhi Liu; Dongchang Sun; Microbial cell factories using Paenibacillus: status and perspectives, Critical Reviews in Biotechnology, 2024,发表, JCR1, IF=9.0, TOP期刊

2. Panhong Yuan; Mengtao Xu, Chengyao Mao, Han Zheng, Dongchang Sun; Dynamically regulating glucose uptake to reduce overflow metabolism with a Quorum-Sensing circuit for efficient synthesis of D-Pantothenic Acid in Bacillus subtilis, ACS Synthesis Biology, 2023,发表, JCR1, IF=4.7, TOP期刊（封面文章）

3. Panhong Yuan; Mengxian Lv; Peng Jin; Miao Wang; Guocheng Du; Jian Chen; Zhen Kang; Enzymatic production of specifically distributed hyaluronan oligosaccharides, Carbohydrate Polymers, 2016, 142: 309-316,发表, JCR1, IF=11.2, TOP期刊

4.  Panhong Yuan; Shixiu Cui; Yanfeng Liu; Jianghua Li; Guocheng Du; Long Liu; Metabolic engineering for the production of fat-soluble vitamins: advances and perspectives, Applied Microbiology And Biotechnology, 2020, 104(3): 935-951,发表, JCR1, IF=5.0, TOP期刊

5. Panhong Yuan; Guoyun Sun; Shixiu Cui; Yaokang Wu; Xueqin Lv; Yanfeng Liu; Jianghua Li; Guocheng Du; Long Liu; Engineering a ComA Quorum-Sensing circuit to dynamically control the production of Menaquinone-4 in Bacillus subtilis, Enzyme And Microbial Technology, 2021, 147(109782): 1-9, 发表, JCR2, IF=3.4

6. Panhong Yuan; Shixiu Cui; Yanfeng Liu; Jianghua Li; Xueqin Lv; Long Liu; Guocheng Du; Combinatorial engineering for improved menaquinone-4 biosynthesis in Bacillus subtilis. , Enzyme And Microbial Technology, 2020, 141(109652): 1-9,发表, JCR2, IF=3.4

7. Panhong Yuan, Xueqin Lv, Yanfeng Liu; Jianghua Li; Long Liu; Guocheng Du; Regulation of plasma membrane homeostasis to increase the accumulation of menaquinone-4 in Bacillus subtilis [J]. Food and Fermentation Industries, 2021, 47(18): 1-7.

8. Jin, P; Kang, Z; Yuan, P; Du, G.; Chen, J., Production of specific-molecular-weight hyaluronan by metabolically engineered Bacillus subtilis 168. Metabolic Engineering, 2016, 35, 21-30.

9. Jin, P; Zhang, L; Yuan, P; Kang, Z.; Du, G.; Chen, J., Efficient biosynthesis of polysaccharides chondroitin and heparosan by metabolically engineered Bacillus subtilis. Carbohydrate Polymers, 2016, 140, 424-432.

10. Hu S, Fei M, Fu B, Yu M, Yuan P, Tang B, Yang H, Sun D. Development of probiotic E. coli Nissle 1917 for β-alanine production by using protein and metabolic engineering. Applied Microbiology And Biotechnology. 2023, 107(7-8):2277-2288.

11. Chen Z, Shen M, Mao C, Wang C, Yuan P, Wang T, Sun D. A Type I restriction modification system influences genomic evolution driven by horizontal gene transfer in Paenibacillus polymyxa. Frontiers Microbiology, 2021, 12:709571.

12. Lv, M; Wang, M; Cai, W; Hao, W; Yuan, P; Kang, Z., Characterisation of separated end hyaluronan oligosaccharides from leech hyaluronidase and evaluation of angiogenesis. Carbohydrate Polymers, 2016, 142, 309-316.

13. Li H, Shen X, Chu Y, Yuan P, Shuai Q. Challenging and new opportunities for prodrug technology. Invest New Drugs. 2025 Feb 18. 

14. Mao C, Zheng H, Chen Y, Yuan P, Sun D. Development of a Type I-E CRISPR-Based Programmable Repression System for Fine-Tuning Metabolic Flux toward D-Pantothenic Acid in Bacillus subtilis. ACS Synth Biol. 2024 Aug 16;13(8):2480-2491. doi: 10.1021/acssynbio.4c00256. Epub 2024 Jul 31. PMID: 39083228.